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Examples of Structure-Based Drug Design

A fine example of structure-based drug design has been reported for the design of an influenza virus neuraminidase inhibitor (see Scheme 11). Neuraminidase is an enzyme expressed on the surface of influenza virions and it is thought to be important for the successful release of progeny. Inhibition of... [Pg.8]

C Flexibility gnd temperature factors Some selected examples of structure-based drug design... [Pg.417]

V SOME SELECTED EXAMPLES OF STRUCTURE-BASED DRUG DESIGN... [Pg.429]

Examples of Structure-Based Drug Design in the Discovery of Marketed Drugs and Advanced Clinical Candidates... [Pg.116]

Distinguishing Molecules of Different Biol< ical Activities and Finding a New Lead Structure - An Example of Ligand-Based Drug Design... [Pg.612]

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Based Drug Design

Bases examples

Design Bases

Design examples

Design structures

Drug structure

Drug structure-based

Example of design

Examples of structures

Structure based design

Structure designable

Structure drug design

Structure-based drug design

Structures of drugs