Evolution of biological macromolecule

Eigen, M. (1971). Self-organization of matter and the evolution of biological macromolecules. Naturwissenschaften, 58, 465-523. 

M. Eigen, Selforganization of Matter and the Evolution of Biological Macromolecules, Naturwissenschaften 58 (10) (1971) 465 523. 

Eigen has also been interested in the chemical basis of the origin of life, which seems to be a very different question from his previous studies, in reality it is not. Two of his papers were named Citation Classics by Current Contents. One paper was Proton-transfer, acid-base catalysis, and enzymatic hydrolysis. Part I elementary processes. An ew. Chem. 1963, 75, 489 Int. Ed. En l. 1964, 5, 1-19. It was one of the most cited papers in the field. The German and the English versions have been cited more than 285 and 965 times, respectively, by 1990. Then Eigen worked on evolution and published another paper, Self-organization of matter and the evolution of biological macromolecules. Naturwissenschafien 1971, 58, 465-523. This paper was the most cited paper in that journal in over 490 publications by 1990. 

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