Evoked potentials, effect

Fukaya C, Katayama Y, Kasai M et al 2003 Evaluation of time-dependent spread of tissue damage in experimentai spinai cord Injury by kllled-end evoked potential effect of high-dose methylprednisolone. 

Yargicoglu P, Agar a, Gumuslu S, Bilmen S and Oguz Y (1999) Age-related alterations in antioxidant enzymes, lipid peroxide levels, and somatosen-sory-evoked potentials effect of sulfur dioxide. Arch Environ Contam Toxicol 37 554-560. 

Recently, there has been a growth of interest in the development of in vitro methods for measuring toxic effects of chemicals on the central nervous system. One approach has been to conduct electrophysiological measurements on slices of the hippocampus and other brain tissues (Noraberg 2004, Kohling et al. 2005). An example of this approach is the extracellular recording of evoked potentials from neocortical slices of rodents and humans (Kohling et al. 2005). This method, which employs a three-dimensional microelectrode array, can demonstrate a loss of evoked potential after treatment of brain tissue with the neurotoxin trimethyltin. Apart from the potential of in vitro methods such as this as biomarkers, there is considerable interest in the use of them as alternative methods in the risk assessment of chemicals, a point that will be returned to in Section 16.8. 

Lasky RE, Maier MM, Snodgrass EB, et al. 1995. The effects of lead on otoacoustic emissions and auditory evoked potentials in monkeys. Neurotoxicol Teratol 17 633-644. 

Lilienthal H, Winneke G. 1996. Lead effects on the brain stem auditory evoked potentials in monkeys during and after the treatment phase. Neurotoxicol Teratol 18 17-32. 

Robinson GS, Baumann S, Kleinbaum D, et al. 1985. Effects of low to moderate lead exposure on brainstem auditory evoked potentials in children Environmental health document 3. Copenhagen, Denmark World Health Organization Regional Office for Europe, 177-182. 

Robinson GS, Keith RW, Bomschein RL, et al. 1987. Effects of environmental lead exposure on the developing auditory system as indexed by the brainstem auditory evoked potential and pure tone hearing evaluations in young children. In Lindberg SE, Hutchinson TC. eds. International Conference on Heavy Metals in the Environment, Vol. 1, New Orleans, LA. September. Edinburgh, UK CEP Consultants, Ltd., 223-225. 

However, the effects were more marked for ginseng and were accompanied by reductions in frontal alpha waveband activity and decreased latency of the P300 component of the auditory evoked potential, a result that suggests more efficient stimulus assessment. 

Evoked potential studies showed that LSD facilitated a PSR this effect was blocked by cyproheptadine (18). The 5-HT agonist quipazine augmented a PSR this effect was blocked by cinanserin but (curiously) not by metergoline (80). Finally, tryptamine (183) and L-tryptophan (19) have been reported to increase PSRs in a cyproheptadine-reversible manner. 

P. A. Bhaskar, S. Vanchilingam, E. A. Bhaskar, A. Devaprabhu, and R. A. Ganesan. Effect of L-dopa on visual evoked potential in patients with Parkinson s disease. Neurology 36 1119-1121 (1986). 

Reeves RR, Struve FA, Patrick G. (1999). The effects of caffeine withdrawal on cognitive P300 auditory and visual evoked potentials. Clin Electroencephalogr. 30(1) 24-27. 

Loring DW, Meador KJ. (1989). Central nervous system effects of antihistamines on evoked potentials. Ann Allergy. 63(6) Pt 2 604-8. 

Effects on electrophysiological parameters (pharmaco-electroencephalo-gram, evoked potentials) polygraphic sleep studies. 

Hegerl, U., Herrmann, W.M., Ulrich, G., Muller-Oerlinghausen, B. Effects of lithium on auditory evoked potentials in healthy subjects. Biol. Psychiatry TJ, 552-555,1990. 

Sanderson G, Scholfield CN (1986) Effects of adenosine uptake blockers and adenosine on evoked potentials of guinea-pig olfactory cortex. Pflugers Arch 406(l) 25-30 Sattin A, Rail TW (1970) The effect of adenosine and adenine nucleotides on the cyclic adenosine 3, 5 -phosphate content of guinea pig cerebral cortex slices. Mol Pharmacol 6(1) 13-23 Sawynok J, Zarrindast MR, Reid AR, Doak GJ (1997) Adenosine A3 receptor activation produces nociceptive behaviour and edema by release of histamine and 5-hydroxytryptamine. Eur J Pharmacol 333(1) 1-7... 

Further support for the potentiating effects of Httexp on NMDAR activity was obtained by Lynn Raymond s and Michael Hayden s laboratories in the analysis of YAC72 HD mouse model (Hodgson et al., 1999). NMDA-evoked currents (Figure 4c, 4d) (Zeron et al., 2002) and NMDA-mediated Ca2+ transients (Zeron et al., 2004) were significantly increased in striatal neurons from YAC72 mouse when compared to wild type controls. Consistent with the HEK293 cells expression... 

---