Euphorbia fidjiana

Many other mellein derivatives have been found. One of the more common is 5-methylmellein (6). It has been isolated from the almond pathogen Fusicoccum amygdali (ref.48), Hypoxylon and Numularia spp. (ref.49, 50), Phomopsis oblonga (ref.14), Valsa ceratosperma (ref.51), plants of Semecarpus spp. (ref.52), fungus-infected wood (ref. 53), and the heartwood of the Fijian species Euphorbia fidjiana (ref.54). 

Atisane is the basic skeleton of various diterpene alkaloids (aconitum-alkaloids) found in the plant families of Ranunculaceae and Garryaceae. (-)-Atisine, as a typical representative, was isolated from the Atis plant Aconitum heterophyllum (Ranunculaceae), which also contains (-)-15,20-dihydroxy-16-atisen-19-oic acid as the lactone (19,20-olide). Erythroxylon monogynum and related speeies are reported to contain (-)-16-atisene. Euphorbiaceae such as Euphorbia acaulis and E. fidjiana produce (-)-16a,17-dihydroxyatisan-3-one. (+)-13-Atisene-16p,17-diol is known as serradiol due to its natural occurrence in Sideritis serrata (Labiatae). 

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