Sideritis serrata

The structure of lagascol (42), from Sideritis serrata,45 was defined by a correlation with the 1 la-alcohol, lagascatriol, previously obtained from this source. 

Beyerenes.—ent-l8- and -19-Hydroxybeyer-15-ene and the 15,16-epoxide have been isolated from Baccharis tola (Compositae), and 1,12- and 1,17-diacetoxyjativatriol have been detected as constituents of Sideritis serrata (Labiatae). 

Atisane is the basic skeleton of various diterpene alkaloids (aconitum-alkaloids) found in the plant families of Ranunculaceae and Garryaceae. (-)-Atisine, as a typical representative, was isolated from the Atis plant Aconitum heterophyllum (Ranunculaceae), which also contains (-)-15,20-dihydroxy-16-atisen-19-oic acid as the lactone (19,20-olide). Erythroxylon monogynum and related speeies are reported to contain (-)-16-atisene. Euphorbiaceae such as Euphorbia acaulis and E. fidjiana produce (-)-16a,17-dihydroxyatisan-3-one. (+)-13-Atisene-16p,17-diol is known as serradiol due to its natural occurrence in Sideritis serrata (Labiatae). 

Source Sideritis serrata Lag. Mol. formula C2QHg2 Mol. wt. 272 Solvent CDC1 ... 

Beyeranes.—Beyeren-19-ol has been isolated73 from Helipterum craspedoides (Compositae). Tartessol, isolated74 from Sideritis grandiflora, is the 14-monoacetate of ent- 14a, 18-dihydroxybeyer-15-ene (75). Tobarrol, ent-12a, 17-dihydroxybeyer-15-ene (76), was isolated45 from S. serrata and related to jativatriol via the 12,17-acetonide. Benuol, isolated from the same source, is ent-la, 17-dihydro xybeyer-15-ene (77) and was interrelated with conchitriol. 

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See also in sourсe #XX -- [ ]

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