Eubacterium, intestinal microflora

Rafii F, Smith DB, Benson RW, Cemiglia CE (1992) Immunological homology among azoreductases from Clostridium and Eubacterium strains isolated from human intestinal microflora. J Basic Microbiol 32 99-105... 

HSDH activities are found rather widely distributed among intestinal bacteria including members of the genera Bacteroides, Eubacterium, Clostridium, Bifidobacterium and Escherichia [25-29]. In the human intestinal microflora, 7a-HSDH appears to be much more widely distributed than 3a-HSDH or 12a-HSDH [17]. Individual species may contain from 1 to 3 different stereospecific HSDHs. However, there is considerable variation between strains regarding the presence and extent of HSDH activity. 

N itrobenz [ajanthracene Bacteroides sp., Butyrivibrio sp., Clostridium clostridiiforme, Clostridium nexile, Clostridium paraputrifiicum, Clostridium perfringens, Eubacterium sp., Eubacterium hadrum. Human, Mouse, Pig and Rat intestinal microflora. 7-Aminobenz[a]anthracene, Benz[a]anthracene7,12-dione. 57. 

Microbial numbers and species diversity increases in the distal small intestine, with facultative anaerobes as well as more strict anaerobic species such as bacteroides, clostridia. Gram positive cocci and bifidobacteria reaching population levels of up to 10 colony forming units (CFU)/mL contents. The colon is the main site of microbial colonization in the gut, and the microflora is dominated by the strict anaerobes. This microflora is made up of Bacteroides spp., Eubacterium spp., Clostridium spp., Eusobacterium spp, Peptostreptococcus spp., and Bifidobacterium spp., with lower population levels of anaerobic streptococci, lactobacilli, methanogens and sulphate-reducing bacteria (Figure 6.2). Climax microbial populations occur (up to 10 cells/g) and estimates of diversity range from 400 to 500 different bacterial species. The facultative anaerobes such as lactobacilli, streptococci/enterococci and the Enterobacteriaceae occur in population levels about 100-1000-fold lower than strict anaerobes (Moore and Holdeman 1975 Conway 1995). 

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