Etodolac pharmacokinetics

Brocks, D. R. and Jamali, F. Etodolac clinical pharmacokinetics, Clin. Pharmacokinet. 1994, 26, 259-274. [Pg.114]

The pharmacokinetics of etodolac have been extensively studied [4, 37-38]. Etodolac possesses a chiral center, and it has been established that the (S)-(+)-etodolac enantiomer possesses almost all of the anti-inflammatoiy property. Pharmacokinetic properties of the non-stereospecific and stereospecific etodolac are described in the following sections... [Pg.142]

Galbraith L A, McKellar Q A 1996 Protein binding and in vitro serum thromboxane B2 inhibition by flunixin meglumine and meclofenamic acid in dog, goat and horse blood. Research in Veterinary Science 61 78-81 Gerring E L, Lees P, Taylor J B 1981 Pharmacokinetics of phenylbutazone and Its metabolites in the horse. Equine Veterinary Journal 13 152-157 Glaser K, Sung M L, O Neill K et al 1995 Etodolac... [Pg.263]

Jamali, F. Mehvar, R. Lemko, C. Eradiri, O. Application of a stereospecific high-performancfe liquid chromatography assay to a pharmacokinetic study of etodolac enantiomers in humems. J.Pharm.Sci., 1988, 77, 963-966... [Pg.592]

Ermer, J.C. Hicks, D.R. Wheeler, S.C. Kraml, M. Jusko, W.J. Concomitant etodolac affects neither the unbound clearance nor the pharmacologic effect of warfarin. Clin.Pharmacol.Ther, 1994, 55, 305-316 [serum nitrazepam (IS) SPE LOD 15 ng/mL pharmacokinetics]... [Pg.1478]

Boni, J. et al., Pharmacokinetic and pharmacodynamic action of etodolac in patients after oral surgery, J. Clin Pharmacol., 39(7) 729-737, 1999. [Pg.54]

Brocks, D.R. Jamah, F. Enantioselective pharmacokinetics of etodolac in the rat tissue distribution, tissue binding, and in vitro metabolism. J. Pharm. Sci. 1991, 80, 1058 1061. [Pg.288]

Boni, J.P. Korth-Bradley, J.M. Richards, L.S. Chiang, S.T. Hicks, D.R. Benet, L.Z. Chiral bioequivalence effect of absorption rate on racemic etodolac. Clin. Pharmacokinet. 2000, 39, 450-469. [Pg.424]

Brocks, D.R. Jamali, F. The pharmacokinetics of etodolac enantiomers in the rat lack of pharmacokinetic interaction between enantiomers. Drug Metab. Dispos. 1990, 18, 471 75. [Pg.426]

Etodolac. Etodolac does not appear to affect the pharmacokinetics of glibenclamide. ... [Pg.497]

A three-way crossover study in 16 healthy subjects found that etodolac 200 mg every 12 hours for 3 days had no effect on the pharmacokinetics or the pharmacological effects of phenytoin (100 mg twice daily for... [Pg.551]

A pharmacokinetic study in patients with rheumatoid arthritis found that etodolac 600 mg daily did not affect the AUC of methotrexate, but the duration of exposure was lengthened (mean residence time increased from... [Pg.650]

An a J-M, Fabre D, BressoUe F, Bolc na C, Alric R, Cocciglio M, Dropsy R, Sany J. Effect of etodolac on methotrexate pharmacokinetics in patients with rheumatoid arthritis. J Rheumatol (1994)21,203-S. [Pg.651]

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