Ethyleneglycol molecular structure

Recently, Dubault et al. (44) tried to dissolve low molecular poly(ethyleneglycol) in the nematic phase of pazoxyanizole. Only very low molecular weights (2,000) could be dissolved up to a maximum of 1% (wt.) concentration. In contrast Noel and Billard (45) have reported complete miscibility of a poly(azomethine) of a low molecular weight (2,000-4,000) with three nematic reference solvents. The nematic solvents and the nematic polymer were characterized by a very similar molecular structure translated into similar solubility parameters, making it the first successful example of application of the compatibility rules to polymeric systems. Substantially more data is needed to answer the question of effectiveness of compatibility rules in the field of macromolecules. 

The template, the functional monomers and the cross-linking monomers are dissolved in a non-polar solvent. The functional monomers and the template form complexes and the strength of these are reflected in the selectivity of the imprinted polymer. The choice of functional monomer is based on the template structure. Functional monomers are chosen for their ability to interact non-covalently with the template molecule. The most frequently used functional monomer so far is methacrylic acid (MAA). Also vinylpyridines have been frequently used. As cross-linking monomers, ethyleneglycol dimethacrylate (EDMA) or trimethylolpropane trimethacrylate (TRIM) are widely used. Several other types of functional and cross-linking monomers have been used in molecular imprinting experiments using the non-covalent approach. The choice of monomers is of course important to the... 

Figure 6 The template theophylline (T) is allowed to interact with the functional monomer methacrylic acid (M) to form a self-assembly. The monomers will interact with theophylline and will form a self-assembly complex mainly based on hydrogen bonding. This self-assembly and the positions of the functional monomers are then frozen and held in place by copolymerization with cross-linker ethyleneglycol dimethacrylate (L). This leads to a rigid polymer scaffold that retains the spatial conformation and thus the specific binding cavity of the original template. After extraction of the template, a molecularly imprinted polymer (MIP) is obtained and the imprinted cavity is able to specifically rebind the template and other, even similar structures are excluded from the binding site cavity.

Oligo(ethyleneglycol) terminated alkane-thiol-based SAMs (OEG-SAMs) on gold is a well known typical example and is the prototype of the biocompatible SAMs. This type of SAMs is intriguing because we can reahze that structural disorder and flexibility of organized surfaces at the molecular... 

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