Ethyl parahydroxybenzoate

BP Ethyl hydroxybenzoate JP Ethyl parahydroxybenzoate PhEur Ethylis parahydroxybenzoas USPNF Ethylparaben... 

Ph. Eur. will change names from time to time. Sometimes it is quite obvious and there is no ambiguity between the old and the new name, just a shift in the alphabetical order (examples are sodium diclofenac which has become diclofenac sodium, ethyl parahydroxybenzoate sodium that has become sodium ethyl parahydroxybenzoate). But sometimes, especially with hydrates (ferrous sulfate is now ferrous sulfate heptahydrate), the substance is a different one and sometimes the name will change completely but the substance remains the same e.g. Glycerol triacetate becomes Triacetin, Chloramine becomes Tosylchloramine sodium. 

Hydroxybenzoie acid ethyl ester Carbethoxyphenol Ethyl parahydroxybenzoate Ethylparaben Nipagin A E 214 (sodium salt E 215). 

To highlight the method development plan, we will look at a series of preservatives known as parabens. These preservatives are used in the cosmetic, pharmaceutical, and food industries and are effective antifungal and antimicrobial agents. Antifungal and antimicrobial activity increases with increasing chain length. Methyl and propyl parabens can be added directly to foodstuffs in most countries, and ethyl paraben is permitted in some countries. They can be incorporated into foods at a maximum level of 0.1%. Parabens do occur naturally, but those used in industry are synthetic analytes produced by the esterification of parahydroxbenzoic acid with a suitable alcohol. For example, methanol would be used in the manufacture of methyl parahydroxybenzoate. We have chosen to look at a subsection of the paraben series that includes... 

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