Planning the Method Development

Once the stability and storage conditions of the analytical standard have been established, experiments can be undertaken to develop the analytical method. The preferred strategy is to keep the method as simple as possible, as each step adds to the complexity when training other analysts, and also each added step potentially adds to the uncertainty budget, which is discussed in Chapter 9. A typical method 

Method development is complete once the method steps have been formalized in a draft method standard operating procedure (SOP) ideally prepared in a standard format such as set out in ISO 78-2 1999, ° and sufficient replicate 

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