Ethyl 4-methoxybenzoate

Ethyl indole-2-carboxylate 4-Methoxybenzoic acid, TFAA, H3PO4 74 [11]... 

C H 3C103 1071-71-2) see Dopexamine Thioctic acid ethyl 5-allyl-2-hydroxy-3-methoxybenzoate... 

The simplest possible use that can be made of the Hammett equation is to calculate k or K for a specific reaction of a specific compound, where this information is not available in the literature, or indeed where the actual compound has not even been prepared yet. Thus it is known that the base-catalysed hydrolysis of ethyl m -nitrobenzoate is 63-5 times as fast as the hydrolysis of the corresponding unsubstituted ester under parallel conditions what then will be the comparable rate for base-catalysed hydrolysis of ethyl p-methoxybenzoate under the same conditions Looking at the table of [Pg.374]

Kindler [Twi., 450( 1), 1926] has studied the alkaline hydrolysis of the ethyl esters of a number of substituted benzoic acids. The m-nitro compound was found to have a rate constant 63.5 times as fast as the unsubstituted compound. What relative rate constant is predicted for the reaction of p-methoxybenzoate by the Hammett equation The value based on experimental results is 0.214. 

Encainide Encainide, 4-methoxy-N-[2-[2-(l-methyl-2-piperidinyl)ethyl]phenyl]-benza-mide (18.1.15), is synthesized by acylating 2-(l-methyl-2-piperidylethyl)aniline with 4-methoxybenzoic acid chloride. The chemical structure of encainide is substantially different than other local anesthetics and antiarrhythmics [25-27]. 

IV,B).617 On demethylation with pyridine hydrochloride, it affords the free phenol which is reported to be unstable.617 A similar demethylation of 4-ethyl-2,3-dimethyl-7-methoxybenzo[ ]thiophene affords the corresponding phenol.616 7-Hydroxybenzo[6]thiophene undergoes a Bucherer reaction to give 7-aminobenzo[6]thiophene.84... 

Carbonation of the lithium derivative of 2-methoxybenzo[6]thio-phene affords the corresponding 3-carboxylic acid.183 2-Methylbenzo-[6]thiophene-3-carboxylic acid has been obtained (45%) by carbonation of 2-benzo[6]thienylmethylmagnesium chloride (Section VI,D, 4).528 re-Butyllithium reacts selectively with the bromine atom in 3-bromo-2-fluorobenzo[b]thiophene to give a product, which on carbonation affords 2-fluorobenzo[6]thiophene-3-carboxylic acid.482 Benzo[6]thiophene-7-carboxylic acid is obtained by reduction of the corresponding thioindoxyl with amalgamated zinc and acetic acid.315 Benzo[6]thiophene-3-carboxylic acid and its 2-ethyl derivative have been prepared in high yield by treatment of the pyridinium salt of the 3-chloroacetyl derivative with alkali.132... 

To a solution of 4-amino-5-chloro-2-methoxybenzoic acid (20.2 g) in methyl isobutylketone (250 ml) and triethyl amine (15.3 ml) was slowly dropped ethyl chloroformate (9.6 ml). The reaction mixture was stirred for 30 min at room temperature. To the formed mixed anhydride was then added l-[3-(4-fluorophenoxy)-propyl]-3-methoxy-4-piperidinamine (28.2 g) and the reaction mixture was stirred for 2 hours at room temperature. Subsequently, the reaction mixture was washed with water (80 ml) and a NaOH solution (6.5% w/v, 50 ml). The organic layer was warmed to 65°C and methanol (50 ml) and water (8.5 ml) were added. The solution was cooled slowly and stirred for 2 days during which crystallisation occurred, yielding benzamide, 4-amino-5-chloro-N-(l-(3-(4-fluorophenoxy)propyl)-3-methoxy-4-piperidinyl)-2-methoxy-, monohydrate, cis- (Cisapride) having a cis/trans ratio higher than 99/1. 

To 2-dimethylamino-6-methoxybenzo-[b]-thiophene (96.5 mmol) dissolved in 200 ml tetrahydrofuran was added 200 ml 1M HCl and the mixture refluxed 3 hours. Once cooled, the layers were separated, the aqueous layer extracted with 300 ml CH2CI2, washed with 250 ml water, dried, and concentrated. The residue was recrystallized using ethyl alcohol and the product isolated in 80% yield, mp = 80-82°C. H- and C-NMR, IR, and elemental analysis data supplied. 

ETHYL METHANESULFONATE see EMF500 ETHYL METHANESULPHONATE see EMF500 ETHYL METHANOATE see EKLOOO ETHYL METHANSULFONATE see EMF500 ETHYL METHANSULPHONATE see EMF500 ETHYL-4-METHOXYBENZOATE see AOVOOO ETHYL-p-METHOXYBENZOATE see AOVOOO ETHYL-2-METHYLACRYLATE see EMFOOO... 

C10H12O4 ethyl 4-hydroxy-3-methoxybenzoate 617-05-0 565.15 50.178 1,2 19790 C10H13NO2 benzenepropanol carbamate 673-31-4 504.48 44.315 2... 

The maximum number of AQ in propylene polymerization by supported titanium-magnesium catalysts may be estimated on the basis of the maximum activity of catalysts and kp values ( 10 l/(mol x s). The initial activity of this catalytic system was as high as 80 kg C3H6/(g Ti x h x atm) (in the presence of Al(i-Bu)3 and ethyl /7-methoxybenzoate), not less than 90% of isotactic polymer being formed. One can conclude that is 0.07 mol/mol Ti. Taking into account Cp, the total number of active centers for this catalyst is 10 % of the content of titanium in the catalyst. These data are close to those obtained in ref (see Table 2). 

Kwok, D I, Outten, R A, Huhn, R, Daves, G D Jr, 8-Ethyl-l-methoxybenzo[ii]naphtho[l,2-lj]pyran-6-one C-glycosides by acid-catalyzed glycosylation, J. Org. Chem., 53, 5359-5361, 1988. 

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