Lamotrigine Ethosuximide

U.S, Expert Panel 2005 Ethosuximide Lamotrigine Valproic acid Lamotrigine... 

Drugs that may affect valproic acid include carbamazepine, charcoal, chlorpromazine, cholestyramine, cimetidine, erythromycin, ethosuximide, felbamate, lamotrigine, phenytoin, rifampin, and salicylates. Drugs that may be affected by valproic acid include carbamazepine, clonazepam, diazepam, ethosuximide, lamotrigine, phenobarbital, phenytoin, tolbutamide, tricyclic antidepressants, warfarin, and zidovudine. 

Anticonvulsant Carbamazepine, ethosuximide, lamotrigine, mesantoin, phenytoin, trimefhadione, valproic acid... 

Myoclonic seizures are best treated with valproate but, as a second choice, with clobazam, clonazepam, ethosuximide, lamotrigine, phenobarbitone, piracetam or primidone. 

Most anticonvulsants are excreted in the breast milk in limited amounts, and their use is not generally a contraindication to breastfeeding. Barbiturates, ethosuximide, lamotrigine, and to a lesser extent carbamazepine and benzodiazepines can reach appreciable serum concentrations in breast-fed infants, who should be carefully observed. 

Absence Valproic acid, ethosuximide Lamotrigine, levetiracetam... 

Noninterfering carbamazepine, carbamazepine dihydrodiol, carbamazepine epoxide, N-desmethylsuximide, ethosuximide, lamotrigine, loreclezole, monohydroxycarba-mazepine, phenobarbital, phenytoin, primidone, valproic acid, vigabatrin... 

Absence seizures are best treated with ethosuximide, valproic acid, and perhaps lamotrigine. For a combination of absence and other generalized or partial seizures, valproic acid is preferred. If valproic acid is ineffective in treating a mixed seizure disorder that includes absence, ethosuximide should be used in combination with another AED. 

At least three drugs are effective against absence seizures. Two are nonsedating and therefore preferred ethosuximide and valproate. Clonazepam is also highly effective but has disadvantages of dose-related adverse effects and development of tolerance. Lamotrigine and topiramate may also be useful. 

For simple and complex partial seizures and secondary generalized tonic-clonic seizures, the first line drugs are - carbamazepine, valproate and phenytoin. Second line drugs include - acetazolamide, clobazam, clonazepam, ethosuximide, felbamate, gabapentin, lamotrigine, levetiracetam, oxacarbamazepine, primidone, tiagabine, topiramate and vigabactin. 

For generalized absence seizures, first line treatment is with valproate or ethosuximide and second line treatment with acetazolamide, clobazam, clonazepam, lamotrigine, phenobarbitone and primidone. 

General—absence Ethosuximide, valproic acid, clonazepam Lamotrigine... 

Absence seizure Abrupt onset of impaired consciousness associated with staring and cessation of ongoing activities typically lasting <30 seconds. Ethosuximide, valproate Lamotrigine... 

Barbiturates phenobarbital 1 Benzodiazepines alprazolam, diazepam, i lorazepam, oxazepam Carbamazepine, ethosuximide, valproic acid, phenytoin, diazepam, lorazepam, gabapentin, lamotrigine, felbamate, topiramate, tiagabin, vigabatrin... 

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