Ethers 2-methoxyethoxy, alcohol

Methoxyethoxy)ethoxy ]-ethanol Acetophenone Methyl benzoate Phenyl acetate Methyl salicylate Benzyl methyl ether Phenethyl alcohol Dimet hylaniline Isoamyl propionate Isoamyl lactate Quinoline Indene... 

Reduction of aromatic carboxylic acids to alcohols can be achieved by hydrides and complex hydrides, e.g. lithium aluminum hydride 968], sodium aluminum hydride [55] and sodium bis 2-methoxyethoxy)aluminum hydride [544, 969, 970], and with borane (diborane) [976] prepared from sodium borohydride and boron trifluoride etherate [971, 977] or aluminum chloride [755, 975] in diglyme. Sodium borohydride alone does not reduce free carboxylic acids. Anthranilic acid was reduced to the corresponding alcohol by electroreduction in sulfuric acid at 20-30° in 69-78% yield [979],... 

Powerful complex hydrides like lithium aluminum hydride in refluxing ether [5i] or refluxing tetrahydrofuran [1017] reduce cyclic anhydrides to diols. Phthalic anhydride was thus transformed to phthalyl alcohol (o-hydroxy-methylbenzyl alcohol) in 87% yield [5i]. Similar yields of phthalyl alcohol were obtained from phthalic anhydride and sodium bis 2-methoxyethoxy) aluminum hydride [544, 969]. 

Hydroxybenzyl alcohols have been converted to dioxepins, as the major product, by forming methoxyethoxy-methyl (MEM) ethers either on the phenolic -OH or on the benzylic -OH and reacting the other -OH group with bromoacetaldehyde dimethyl acetal, followed by treatment with BF3-OEt2 (Scheme 9) <2004T11453>. 

Na[AlH2(OCH2CH20CH3)2l (RED-AL) (sodium bis-[2-methoxyethoxy]-aluminium hydride) Ethers, toluene -78 to RT ester — alcohol ketone — alcohol aldehyde — alcohol alkyl halide — alkane epoxide — alcohol Dt,U-unsaturated enone —> allvlic alcohol... 

Two novel complex hydrides are likely to find applications in steroid chemistry lithium perhydro-9b-boraphen yl hydride affords unusually high proportions of axial alcohols in model compounds sodium bis(methoxyethoxy)aluminium dihydride, Na (MeOCH2CH20)JAlH2, a very safe and convenient substitute for lithium aluminium hydride, readily reduces not only ketones but also acids, nitro-compounds, oximes, amides, lactones, etc. An improved procedure for Clemmensen reduction of steroid ketones involves saturating an ethereal solution with hydrogen chloride while stirring with zinc. 5a-Cholestane was obtained from the 3-one in 89% yield. ... 

Methyl diglycol [111-77-3] [2-(2-methoxyethoxy)ethanol, diethylene glycol monomethyl ether] is miscible with water and most organic solvents. It is a good solvent for cellulose nitrate, colophony, phenol-, urea-, and melamine-formaldehyde resins, alkyd resins, alcohol-soluble maleate resins, ketone-formaldehyde... 

CAS 111-77-3 EINECS/ELINCS 203-906-6 Synonyms DEGME DIethylene glycol methyl ether DIethylene glycol monomethyl ether Ethanol, 2-(2-methoxyethoxy)- 2-(2-Methoxyeth-oxy) ethanol Methyl Carbltol Methyl digol Classification Aliphatic ether alcohol Empirical C5H12O3 Eormula CH30CH2CH20CH2CH20H... 

CAS 111-77-3 EINECS/ELINCS 203-906-6 Synonyms DEGME Diethylene glycol methyl ether Diethylene glycol monomethyl ether Ethanol, 2-(2-methoxyethoxy)- 2-(2-Methoxyethoxy) ethanol Methyl Carbitol Methyl digol Classification Aliphatic ether alcohol Empin cal C5H12O3 Formula CH3OCH2CH2OCH2CH2OH Properties Water-wh. liq. mild pleasant odor sol. in water, alcohols, glycerol, ether, acetone misc. with most org. soivs. m.w. 120.17 dens. 1.0211 (20/4 C) vapor pressure 0.2 mm Hg (20 C) m.p. -85 C b.p. 194 C flash pt. 93.3 C ref. index 1.4264(27 C)... 

Cleavage of Acetals. Cyclic and acyclic acetals react with Mc2BBr at -78 °C to generate the parent aldehydes and ketones in excellent yield (e.g. eq 6). Primary, secondary, and tertiary (2-methoxyethoxy)methyl (MEM), methoxymethyl (MOM), and (rnethylthio)methyl (MTM) ethers also react at —78 °C to give, after aqueous workup, the corresponding alcohol. It is interesting to note that even tertiary MEM ethers cleanly regenerate the... 

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