4-Methyl-acetophenone

Dlchloro 2-hydroxy-6-methyl acetophenone (2) and 6,8-0lchloro>2,5-dlRiethylchromone (3) A mixture of 2,4-dichioro 5-methylphenyl acetate 1 (39 6 g,... 

Natrium-trifluoracetoxy-trihydrido-borat reduziert O-Alkyl-oxime in siedendera Tetrahydrofuran zu prim. Aminen. So erhalt man z. B. aus O-Methyl-acetophenon-oxim 1 -Phenyl-dthylamin zu 90% d.Th.. ... 

Kukol, A. Strehle, F. Thielking, G. Grutzmacher, H.-F. Methyl Group Effect on the Proton Affinity of Methylated Acetophenones Studied by Two Mass Spectrometric Techniques. Org. Mass Spectrom. 1993,25,1107-1110. 

Several researchers have investigated the photoenolization of various o-methyl acetophenone and o-methyl benzophenone derivatives. The mechanism of photoenolization of o-methyl benzophenone, 1, has been studied with laser flash photolysis and can be described as follows (Scheme 2) Irradiating 1 forms its first... 

The photoreactivity of o-methyl acetophenone 11 has been studied exten-sively it is somewhat different from 1 because the singlet excited ketone (Sik) in 11 intersystem crosses to its triplet state in less than quantitative yields, as observed for 1 (Scheme 8). Thus, Sik in 11 decays by both intramolecular H-atom abstraction to form exclusively photoenol Z-13 and intersystem crossing to Tik of 11. Haag et al. estimated that Tik of 11 has a lifetime of 10 ns in benzene and decays by intramolecular H-atom abstraction to form biradical 12. The maximum... 

In 1978, Bergmark determined that photorelease can also take place when the a-position of an o-methyl acetophenone has a good leaving group, such as a chlorine atom. ° He showed that photolysis of 33 in benzene resulted in the formation of 36, whereas in methanol, both 36 and 37 were formed (Scheme 24). In 1985, Bergmark followed up his earlier work with a more detailed study and showed that the elimination of a chorine atom from 33 took place in high quantum yields, especially in methanol. Thus, Bergmark concluded that both E-34 and Z-34 released their chlorine atoms. Additionally, he theorized that the release from Z-34 took place via solvolysis to from carbocation 35. 

Solvent Viscosity, cP, 30°C Quantum yields of 2-hydroxy-5-methyl acetophenone (56) Formation of 4-methylphenol (19)... 

C9H10O, Mr 134.18, mp 28 °C, Z> ioi.3kPa 226 °C, df 1.0051, nf 1.5335, has been identified in Brazilian rosewood oil and in pepper. It occurs as colorless crystals with a flowery-sweet odor that is milder than that of acetophenone. 4-Methyl-acetophenone is prepared from toluene and acetic anhydride or acetyl chloride by... 

Under the same general conditions, satisfactory yields of other acetophenones may be obtained. Thus, from 281 g. of chlorobenzene, 750 g. of aluminium chloride, and 205 g. of acetic anhydride, a consistent yield of 285 to 300 g. (70-73 per cent of the theoretical amount) of -chloroacetophenone, boiling at i24-i26°/24 mm. and melting at 20-21°, is obtained. Similarly, acetophenone may be obtained in 76-83 per cent yields, -methyl-acetophenone in 85-89 per cent yields, and />-methoxyacctophe-none in 90-94 per cent yields. 

N. P, S COMPOUNDS Acetophenone Methyl acetophenone Phthalic Anhydride Methyl benzoate Indanone Dibenzofuran Diethyl phthal ate Di butylphthalate Di i sobutylphthalate Di (2-ethyl hexyl) phthal ate Diphenyl amine... 

Syringa aldehyde para-Tolyl aldehyde Methyl acetophenone Cuminic aldehyde... 

Methyl acetophenone benzofenap Methyl allyl chloride benfuresate, carbofuran... 

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