Estrus cycle protein

In rats orally administered an acetone extract of fennel at doses of 0.5 to 2.5 mg/kg daily for 14 days, dose-dependent induction of the estrus cycle and increased weights of mammary glands, endometrium, cervix, and vagina were observed in females. In males, a decrease in total protein concentration in the testes and vas deferens and an increase in the seminal vesicles and prostate gland were observed after doses of 1.5 or 2.5 mg/kg (Malini et al. 1985). 

The protein requirement for reproduction varies in different species. In the rat a dietary protein content of 5 per cent or less in the diet was found insufficient for ovulation and reproduction (19, 20). Macomber (21), however, stated that the reduction in the amount of protein had little effect upon conception and pregnancy beyond a reduction in fertility, and a slight effect upon the weight of the young even when the reduction was extreme. There Is good evidence that qualitative protein deficiency interferes vdth reproduction, since diets containing wheat (9) or gliadin (22,23) as the main sources of protein lead to cessation of estrus cycles. Addition of casein or lysine restores ability to reproduce. 

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