Estimation of Exposure to Dioxin-Like Compounds Using Sediments, Caged Fish, and SPMDs

ESTIMATION OF EXPOSURE TO DIOXIN-LIKE COMPOUNDS USING SEDIMENTS, CAGED FISH, AND SPMDs 

0 White Rock Creek West Fork Trinity River Trinity River below Dallas 

A number of toxicologically active 2,3,7,8-substituted PCDDs and PCDFs, planar PCBs and PCDD, PCDF, and PCDT homologs were measured in fish, SPMDs, and sediments. Only two target compounds exceeded the detection limits of 0.2-1 pg g in SPMD field blanks (see definition in Chapter 5). These exceptions were octachlorodibenzo-p-dioxin (OCDD) and octachlorodibenzofuran (OCDF) which were present in SPMDs at about 5 pg g However, negative 

USING SPMDs IN CONJUNCTION WITH BIOASSAYS AND CHEMICAL ANALYSIS TO CHARACTERIZE TOXIC POLLUTANTS 

These data indicate that hydrophobic chemicals with estrogenic and EROD-inducing potential are widespread in this ecosystem and are readily bioavailable to aquatic organisms living in the system. By incorporating the YES, the recently developed yeast androgen screen, and the EROD assays (Rastall, 2004b) into exposure assessment approaches, a more complete picture of the potential toxicity 

---