Planar PCBs

Proposed toxicity equivalency value (TEF) relative to 2,3,7,8-TCDD of non-ortho, mono-ortho, and di-ortho planar PCBs... 

Mammals Beluga whale, Delphinapterus leucas Found dead in St. Lawrence River estuary 1987-90 blubber 2,3,7,8-TCDD equivalents (due primarily to planar PCBs) Females 330 FW 35... 

Mammal-derived TEFs underestimate the potency of planar PCB mixtures in fish (Newsted et al. 1995). TEF values of non-ort/zo-PCB congeners based on mortality of rainbow trout in early life stages are as much as 1000 times lower than TEFs proposed for human risk assessment (Walker... 

Group I planar PCBs are 10 times more toxic and 100 times more effective as inducers of cytochrome P-450c-dependent monooxygenase and 70 times more effective in competitively displacing 2,3,7,8-TCDD from a rat cytosol receptor protein than Group II planar PCBs (Table 24.4 ... 

New Bedford Harbor, Massachusetts vs. two control sites in Rhode Island spring, 1988 liver Planar PCBs ... 

Eisler, R. and A. A. Belisle. 1996. Planar PCB Hazards to Fish, Wildlife and Invertebrates A Synoptic Review. U.S. Natl. Biol. Serv. Biol. Rep. 31. 75 pp. 

Theelen, R.M.C., et al. Intake of 2,3,7,8-tetrachlorodibenzo-p-dioxin, substituted dioxins, furans, and planar PCBs from food in the Netherlands median and distribution, Chemosphere. 27, 1625, 1993. 

Figure 3.4 Activation energies of contaminant sampling by SPMDs as a function of molar volume (LeBas method). PAHs—filled circles Huckins et al. (1999) filled squares Booij et al. (2003a) pesticides—open circles Huckins et al. (2002b) chlorobenzenes and PCBs—open squares Booij et al. (2003b) planar PCBs— triangles Rantalainen et al. (2000) and PCDD/Fs—asterisks Rantalainen et al. (2000).

A number of toxicologically active 2,3,7,8-substituted PCDDs and PCDFs, planar PCBs and PCDD, PCDF, and PCDT homologs were measured in fish, SPMDs, and sediments. Only two target compounds exceeded the detection limits of 0.2-1 pg g in SPMD field blanks (see definition in Chapter 5). These exceptions were octachlorodibenzo-p-dioxin (OCDD) and octachlorodibenzofuran (OCDF) which were present in SPMDs at about 5 pg g However, negative... 

Hoogenboom, R., Portier, L., Onstenk, C., Polman, T., Hamers, A., Traag, W. (2000). Determination of dioxins and planar PCBs in fish using the GC/MS and CALUX bioassay Introduction of the screening approach for control purposes. Organohalogen Compounds 45 180-183. 

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