Esophagus bronchus

If a-hydroxylation of NPYR is its mechanism of activation, one would expect the formation of carcinogen-DNA adducts containing a 4-oxobutyl- or related residue. Adducts have been isolated from the liver RNA of NPYR treated rats, but their structures have not been determined (25). Carcinogen DNA adducts have also been isolated from cultured human esophagus, colon, and bronchus (26, 27, 28). 

Autrup, H., Grafstrom, R.C., Brugh, M., Lechner, J.F., Haugen, A., Trump, B.E, and Harris, C.C. (1982). Comparison of benzo[a]p3rtene metabolism in bronchus, esophagus, colon, and duodenum from the same individual, Cancer Res. 42,934. 

B. Perform endotracheal intubation if personnel trained in the procedure are available. Intubation of the trachea provides the most reliable protection of the ainvay, preventing aspiration and obstmcfion and allowing for mechanically assisted ventilation. However, it is not a simple procedure and should be attempted only by those with training and experience. Complications include vomiting with pulmonary aspiration local trauma to the oropharynx, nasopharynx, and larynx inadvertent intubation of the esophagus or a main-stem bronchus and failure to intubate the patient after respiratory arrest has been... 

Bronchopulmonary foregut malformations are rare congenital anomalies that are characterized by a fistula between an isolated portion of respiratory tissue and the foregut (Srikanth et al. 1992). Of these malformations, the esophageal bronchus communicating with the lower esophagus is the most common. Com-... 

Fig. 2.15. Esophageal bronchus. Barium esophagram demonstrates that the right main bronchus arises from the esophagus. The right lung is completely opacified...

Lung and Bronchus Prostate Colon and Rectum Pancreas Leukemia Esophagus Liver and Intrahepatic Bile Duct Non-Hodgkin Lymphoma Urinary Bladder Kidney and Renal Pelvis... 

The metabolism and binding to DNA of BaP has also been studied in cultured human colon and esophagus (16, 179). Metabolites included the 7,8- and 9,10-dihydrodiols, 7,8,9,10-tetraols, and conjugates. The relative distribution of metabolites varied among individuals. The major DNA adduct was 5 (Fig. 4). Thus, the metabolic pathways and activation of BaP were similar in bronchus, esophagus, and colon. 

Esophagus cancer Rectum cancer Colon cancer LarjTLX cancer Bronchus cancer Breast cancer Breast cancer... 

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