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Epitope scanning mutagenesis

Gunningham, B. C., and Wells, J. A. (1989). High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis. Science 244, 1081-1085. [Pg.166]

Pal G, Fong SY, Kossiakoff AA, Sidhu SS. Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis. Protein Sci. 2005 14 2405-2413. Conlon JM. Evolution of the insulin molecule insights into structure-activity and phylogenetic relationships. Peptides 2001 22 1183-1193. [Pg.714]

Other, perhaps alternative, approaches that could be used for epitope mapping include homolog-scanning mutagenesis (5), which could also be a means of complementing the secondary structure predictions. This involves the synthesis of an array of small peptides that completely span the protein... [Pg.107]

See other pages where Epitope scanning mutagenesis is mentioned: [Pg.250]    [Pg.271]    [Pg.250]    [Pg.271]    [Pg.78]    [Pg.154]    [Pg.156]    [Pg.222]    [Pg.2337]    [Pg.88]    [Pg.89]    [Pg.154]    [Pg.156]    [Pg.222]    [Pg.250]   
See also in sourсe #XX -- [ Pg.2 , Pg.271 ]



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