Epilepsy research

Brodie MJ and Whitehead J (2006) Active control comparisons the ideal trial design Epilepsy Research, 68, 70-73... 

Straub, H., Kohling, R., Hohling, J.-M., Rundfeldt, C., Tuxhorn, I., Ebner, A., Wolf, P., Pannek, H., Speckmann, E.-J. Effects of retigabine on rhythmic synchronous activity of human neocortical slices, Epilepsy Research 2001, 44, 155-165. 

FIGURE 63.4. Experimental design revealing anticonvulsant effects of diazepam and pentobarbital in epilepsy research (A). Anticonvulsant effects achieved by triple regimen when administered 30-40 min after onset of seizures (B). 

Moraes ME, Galvis-Alonso OY, Garcia-Cairasco N. Audiogenic kindling in the Wistar rat a potential model for recruitment of limbic structures. Epilepsy Research 2000 39 251-259. 

Volk, H.A., Potschka, H., and Loscher, W. (2004) Increased expression of the multidrug transporter P-glycoprotein in limbic brain regions after amygdala-kindled seizures in rats. Epilepsy Research, 58 (1), 67-79. 

Benedetti, M. S., Whomsley, R., Espie, P., and Baltes, E. (2004) The role of the efflux transporter P-glycoprotein (P-gp) on the disposition of antiepileptic drugs implications for drug interactions. In Focus on Epilepsy Research, Benjamin Shawn, M., (ed.), Nova Science, New York, pp. 199-220. 

Pledger G (2001) Proof of efficacy trials choosing the dose. Epilepsy Research 45 23-28 discussion 29-30. 

Croucher, M., Krogsgaard-Larsen, P., Labouta, 1. M. and Meldrum, B. GABA uptake inhibitors as experimental tools and potential drugs in epilepsy research, in Neurotransmitters, Seizures and Epilepsy, MorseUi, R, Lloyd, K. G., Loscher, W., Meldrum, B. S. and Reynolds, E. H., Eds., Raven Press, New York, 1981, p. 23. 

Lukasiuk, K., and Pitkanen, A. 2004. Large-scale analysis of gene expression in epilepsy research is synthesis already possible Neurochem Res 29(6) 1169-1178 Lynch, M., Sayin, U., Bownds, J., JanumpaUi, S., and Sutula, T. 2000. Long-term consequences of early postnatal seizures on hippocampal learning and plasticity. Eur J Neurosci 12(7) 2252-2264... 

Botez, M.I., Botez, T., Ross-Chouinard, A., and Lalonde, R., 1993. Thiamine and folate treatment of chronic epileptic patients a controlled study with the Wechsler IQ scale. Epilepsy Research. 16 157-163. 

Verrotti, A., Pascarella, R., Trotta, D., Giuva, T., Morgese, G., and Chiarelli, F., 2000. Hyperhomocysteinemia in children treated with sodium valproate and carbamazepine. Epilepsy Research. 41 253 257. 

THERAPEUTIC MEASURES Double therapy in epilepsy research... 

---