Epidermal growth factor comparison

Brock R, Hamelers IHL, Jovin TM. Comparison of fixation protocols for adherent cultured cells applied to a GFP fusion protein of the epidermal growth factor receptor. Cytometry 1999 35 353-362. 

In comparison to the level of cellular serine or threonine phosphorylation, protein tyrosine phosphorylation occurs at quite low levels in normal cells but dramatically increases upon oncogenic transformation or stimulation. Since the first discovery in 1978 that the transforming protein from Rous sarcoma virus (pp60vsrc) exhibited intrinsic kinase activity/5 protein kinase activity has also been shown to be inherent to other growth factor receptors such as epidermal growth factor receptor and the insulin receptor,[6 91 and to involve autophosphorylation processes. The diverse biochemical activity exhibited by protein tyrosine phosphorylation has stimulated the development of chemical methods for the preparation of phosphorylated peptides for use as substrates in elucidating the biochemical and physiological activity of phosphorylated site(s). 

Hirsch FR, Dziadziuszko R, Thacher N, et al. Epidermal growth factor receptor immunohistochemistry comparison of antibodies and cutoff points to predict benefit from gefitinib in a phase 3 placebo-controlled study in advanced nonsmall-cell lung cancer. Cancer 2008 112 1114-21. 

Neal, D. E., Marsh, C., Bennett, M. K, Abel, P. D., Hall, R. R., Sainsbury, J. R., and Harris, A. L. (1985). Epidermal-growth-factor receptors in human bladder cancer Comparison of invasive and superficial tumours. Lancet. 1, 366-368. 

Hopkins, C. R., Miller, K., and Beardmore, J. M. (1985) Receptor-mediated endocytosis of transferrin and epidermal growth factor receptors a comparison of constitutive and ligand-induced uptake. J Cell Sci Suppl 3, 173-186. 

Neal, D.E. et al.. Epidermal-growth-factor receptors in human bladder cancer comparison of invasive and superficial tumours. Lancet, 1, 366, 1985. 

Griinewald, K., Haun, M., Urbanek, M. et al. (2000) Mammaglobin gene expression a superior marker of breast cancer cells in peripheral blood in comparison to epidermal-growth-factor receptor and cytokeratin-19. Lab Invest, 80, 1071-1077. 

Figure 5-1. Comparison of the amino acid sequences of human urogastrone and mouse epidermal growth factor (EGF), with noncorresponding residues enclosed. (From Gregory H. Isolation and structure of urogastrone and Its relation to epidermal growth factor. Nature 257 325-327, 1975. Reproduced by permission from Nature, Vol 257, pp 325-327. Copyright 1975 Macmillan Magazines Ltd.)...

Fujino S, Enoldbori T, Tezuka T, Asada Y, Inoue S, Kato H, Mori A. A comparison of epidermal growth factor receptor levels and other prognostic parameters in non-small cell lung cancer. Eur J Cancer 1996 32A 2070-4. 

Wright, TM, Rangan, LA, Shin, HS and Raben, DM (1988) Kinetic analysis of 1,2-diacylglycerol mass levels in cultured fibroblasts. Comparison of stimnlation by alpha-thrombin and epidermal growth factor. Journal ofBiological Chemistry, 263,9374— 9380. 

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