Ephedrine Coffee

The Mormons were introduced to ephedra by Indians when they arrived in Utah. They used it as an alternate to tea and coffee, ironically, because their religious views prohibited use of those stimulants. Ephedra might be the oldest known human stimulant, because remains of the plant were discovered in a fifty thousand-year-old Neanderthal grave in Iraq. Modern medical use of ephedra began with the identification of the alkaloid ephedrine in 1923. 

CNS, smooth muscle T diuresis X- pit aggregation Available forms Daily t doses w/ max 3 g PO daily Contra Avoid in PRG lactation, CAD, hyperthyroidism, anxiety disorders d/t high, caffeine content Notes/SE Insomnia, tach, anxiety, N/V, HA, HTN, Sz Interactions T Effects OF anticoagulants, anti-pits, BBs, bron-choclilators T risk of hypertensive crisis W/ MAOIs T effects W/ cimetidine, ciprofloxacin, ephedrine, hormonal contraceptives, dieophylline, cola, coffee X-effects OF adenosine, antihypertensives, benzodiazepines, Fe, X- effects W/ smoking EMS Tinctures contain EtOH may exacerbate GI disorders HTN T effects of anticoagulants and BBs... 

For most substances, just their presence in a urine sample means a positive result. Other substances must be present in an amount higher than a certain threshold. According to Dr. Ayotte, a male athlete would have to consume "10 very strong French coffees within 15 min" to go over the 12 mg/L limit for caffeine. Ephedrines and pseudoephedrines, two decongestants that are found in cough remedies and that act as stimulants, have a cut-off level. This allows athletes to take them up to one or two days before a competition. 

Additive stimulant effects of caffeine Caffeine is present in many products that contain ephedra alkaloids, and those who take these products might also be consuming considerable quantities of caffeine in coffee, tea, and soft drinks. Caffeine can enhance the undesirable effects of ephedrine on the heart, blood supply system, and brain function. 

To extract the ephedrine from the pills, the first thing which must be done is to grind them into a fine powder. This pulverization must be thorough in order to ensure complete extraction of the ephedrine from the filler matrix in which it is bound. A blender does a fine job of this procedure, as will certain brands of home coffee grinders. 

Fundamentally, there are only two ways to treat obesity reduce El and increase EE. Thermogenesis and fat oxidation are to a large extent under the control of the sympathetic nervous system and its neurotransmitter norepinephrine after a rational approach for obesity management. In this context, there has been much interest in the potential thermogenic effects of many compounds extracted from plants, namely, caffeine from coffee and tea, ephedrine from ephedra, and capsaicin from pungent spices, largely because of their potential to modulate catecholamine release and activity. ... 

Alkaloids are amines found in the leaves, bark, roots, or seeds of many plants. Examples include caffeine (found in tea leaves, coffee beans, and cola nuts) and nicotine (found in tobacco leaves). Nicotine causes brain cells to release dopamine and endorphins, compounds that makes us feel good, thereby making nicotine addictive. Ephedrine, a bronchodilator, is an alkaloid obtained from Ephedra sinica, a plant found in China. Morphine is an alkaloid obtained from opium, a milky fluid exuded by a species of poppy (page 3). 

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