Obesity management

Pharmacology Orlistat is a reversible lipase inhibitor for obesity management that acts by inhibiting the absorption of dietary fats. It exerts its therapeutic activity in the lumen of the stomach and small intestine. 

Drew, B. S., Dixon, A. F., and Drew, J. B. (2007) Obesity management update on orlistat. Vase. Health Risk Manag. 3, 817-821. 

Astrup A, Lundsgaard C. What do pharmacological approaches to obesity management offer Linking pharmacological mechanisms of obesity management agents to clinical practice. Exp Clin Endocrinol Diabetes 1998 106(Suppl 2) 29-34. 

We have witnessed lifestyle drugs in the form of orlistat (Xenical, Roche) prescribed for obesity management (Exhibit 2.10), and growth hormones have been promoted for enhancement of muscle tone and youthful vitality... 

Fundamentally, there are only two ways to treat obesity reduce El and increase EE. Thermogenesis and fat oxidation are to a large extent under the control of the sympathetic nervous system and its neurotransmitter norepinephrine after a rational approach for obesity management. In this context, there has been much interest in the potential thermogenic effects of many compounds extracted from plants, namely, caffeine from coffee and tea, ephedrine from ephedra, and capsaicin from pungent spices, largely because of their potential to modulate catecholamine release and activity. ... 

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