EP reagent

Fomaldehyde (Marquis [ii] and Prochazka reagent), furfural, 4-methoxybenzalde-hyde, 4-(dimethylamino)-cinnamaldehyde and 4-(dimethylamino)-benzaldehyde (Ehrlich s, Van Urk s, Morgan-Elson or EP reagents) react according to this scheme with... 

Note The EP reagent can be used for the specific detection of matricin in chamomile extract [1]. 

Hydroxylamine/ferric chloride Sakaguchi reagent EP-reagent... 

Detection of proazulene (Malricariae flos) After heating at 100 C for 5-10 min, proazulene gives a blue-green colour (vi.s.) The blue colour of azulene is inten.sified by EP reagent. 

Dimethylaminobenzaldeliyde-acetie aeid-phosphorle acid (EP-reagent) for proazulenes and azulenes. 

Today, nearly every important reagent or method reported in the literature has a patent or patent application associated with it, especially if it has potential commercial value. A search of the patent databases, such as the United States Patent and Trademark Office (http //www. uspto.gov/) or the European Patent Office (http //ep.espacenet.com/) for key words or the potential names of inventors can provide a list of any existing issued patents or patent applications related to a bioconjugate technique or compound. In addition, a fee-based service such as Delphion is particularly effective at finding patents related to any subject matter (http //www. delphion.com/). 

Scheme 7-15 shows the significant improvement in overall stereoselectivity, due mainly to the adoption of the newly developed Sharpless asymmetric ep-oxidation. Compounds a-epoxy-67 and //-epoxy-67 can be readily obtained from 53 via the Sharpless reaction. Isomers of compounds 57 are then constructed via regioselective ring opening with a copper reagent. 

The electrogeneration of [(TPP)Co] from (TPP)Co, and the reaction of this species with CHjI can be followed by cyclic voltammetry as shown in Figures lc and Id. In the absence of any added reagent, there are two reversible reduction waves which occur at Ei/2 = 0.85 jind -1.86 V (see Figure lc). These are due to the formation of [(TPP)CoJ and [(TPP)Co]2-, where the second reduction has occurred at the porphyrin ir ring system. The first reduction of (TPP)Co is not reversible in the presence of CH3I, and occurs at Ep = -0.86 V (see Figure Id). A new reversible reduction also appears at Ej/2 = -1.39 V. This process is due to (TPP)Co(CHj) which is formed as shown by Equation 8. The formation of (TPP)Co(CHj) as the final product of the electrosynthesis was confirmed by spectroelectrochemical experiments which were carried out under the same experimental conditions(26). 

Usefulness of different reagents using contrasting conditions for the same synthetic St ep. ... 

The Haldane equation does not relate the equilibrium constant between ES and EP to that between S and P in solution. The equilibrium constant for the enzyme-bound reagents is often very different from that in solution for several reasons ... 

The selectivity of the addition of various reagents to 1,2,3-triazoles has been studied by Tanaka and Miller.160 Treatment of 210 with EP in acetone containing triethylamine gave equal quantities of the adducts 211 and 212. With DMAD the Michael adduct 213 was obtained. 4-Phenyltriazole (214) with EP and sodium methoxide gave 215, and the authors were unable to find any products derived from attack at N-l or N-3. 

PMHS corresponding polymeric reagent (PMHS, polymethylhydrosiloxane), a substantial rate increase was observed over the monomeric model (complete reduction of acetophenone in less than 1 min with PMHS vs. only 60% conversion in 1 h with (EtO)2SiHMe) [55]. The related hydrosilylation of 86 by chiral PTC uses an interesting ep/iedra-derivedhalometallated catalyst 25 (Scheme 10.12) [56],... 

Dyatkin BL, Mochalina EP, Knunyants IL (1969) Reactions of Fluoroolefins with Electrophilic Reagents. In Tarrant P (ed) Fluorine Chemistry Reviews. Marcel Dekker Inc, New York and Basel, vol 3, p 45... 

Analytical Reagent ANALAR dichloromethane was dried by storing over 4A sieves. The checkers purchased the EP grade solvent from Wako Pure Chemical Industries. 

The reagents used for the analysis are ultra pure (EP) grade acetyl bromide (Tokyo Chemical Industries), 2M sodium hydroxide, acetic acid (BDH Analar grade or equivalent) and analytical grade 70% perchloric acid. The acetyl bromide should be stored under nitrogen when not being used (Wu and Wilson 1967). 

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