Enterohepatic circulation, folate vitamin

A further problem with studies in patients maintained on long-term total parenteral nutrition is that they are not normal healthy subjects - there is some good medical reason for their treatment Furthermore, they will have little or no enterohepatic recirculation of vitamins, and hence may have considerably higher requirements than normal there is considerable enterohepatic circulation of folate (Section 10.2.1) and vitamin B12 (Section 10.7.1). 

Vitamin M Vitamin M is also called pteroylglutaminic add or folic acid. It was isolated from yeast extract by Wills in 1930. Its structure was described by Anger in 1946. Folic add is made up of pteridine + p-aminobenzoic add + glutamic add. There are several known derivatives, called folates, which are capable of mutual restructuring. The coenzyme tetrahydrofolic acid, which plays a role in many biochemical reactions, is formed with the help of Bi2. Around 50% of total body folate are stored in the liver. A folate-binding protein (FBP) is available for transport. Folate undergoes enterohepatic circulation. The release of folate from the liver cells is stimulated by alcohol, which increases urine excretion. Folate deficiency (e.g. in the case of alcohol abuse) is accompanied by the development of macrocytosis. 

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See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

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