Enterococcus faecalis aminoglycoside-resistant

Chiew YF, Hall LM (1998) Comparison of three methods for the molecular typing of Singapore isolates of enterococci with high-level aminoglycoside resistances. J Hosp Infect 38 223-230 Clewell DB (1993) Bacterial sex pheromone-induced plasmid transfer. Cell 73 9-12 Coburn PS, Gilmore MS (2003) The Enterococcus faecalis cytolysin a novel toxin active against eukaryotic and prokaryotic cells. Cell Microbiol 5 661-669... 

After culture and sensitivity results are obtained, antibiotic therapy should be adjusted appropriately (Fig. 45-5). If the patient does not show signs of clinical improvement within 72 hours after antibiotic treatment is initiated, the culture should be repeated and the patient re-evaluated. For streptococcal or enterococcal peritonitis, IP ampicillin (125 mg/L in each exchange) is the preferred treatment. For Enterococcus, the addition of an aminoglycoside, depending on sensitivities, may be warranted for synergy. In addition, if the Enterococcus is resistant to both ampicillin and vancomycin, linezolid or quinupristin/dalfopristin are recommended. However, quinupristin/ dalfopristin is not effective against E.faecalis. 

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