Enterococci drug-resistant

In recent years multi-drug resistance has increased among certain pathogens. These include aureus, enterococci andM. tuberculosis. Staphylococcus aureus... 

Simonsen G.S., H. Haaheim, K.H. Dahl, H. Kruse, A. Lovseth, O. Olsvik, and A. Sundsfjord (1998). Transmisssion of vanA-type vancomycin-resistant enterococci and vanA resistance elements between chicken and humans at avoparcin-exposed farms. Microbial Drug Resistance—Mechanisms Epidemiology and Disease 4 313-318. 

Vancomycin [van koe MYE sin] is a tricyclic glycopeptide that has become increasingly important because of its effectiveness against multiple drug resistant organisms such as methicillin-resistant staphylococci. The medical community is presently concerned about reports of emergence of vancomycin resistance in these strains as well as the enterococci. 

A major problem with antibiotics is that their overuse and improper use have led to the development of drug resistant bacteria and thus an increased number of infections with opportunistic bacteria, such as enterococci, coli-forms, pseudomonads, streptococci which are versatile and capable of becoming multidrug resistant. With this background, it may be said that searching for newer antimicrobial substances would be a promising line of research in the field of clinical microbiology. 

They are new drugs that are used parenterally in severe infections caused by vancomycin-resistant staphylococci (VRSA) and enterococci (VRE), as well as other drug-resistant grampositive cocci. 

Ampicillin is the standard penicillin that has broad-spectrum activity, and is the drug of choice for enterococci sensitive to penicillin. Amoxicillin is frequently used as well. Increasing E. coli resistance has limited amoxicillin use in acute cystitis. Amoxicillin-clavulanate is empirically preferred due to resistance. 

This drag is resistant with respect to a broad spectrum of beta-lactamases. Its spectrum of activity is analogous to that of the third-generation cephalosporin cefotaxime (32.1.2.56), although it is more active with respect to some staphylococci, enterococci, and also a few enterobacteria. Synonyms of this drug are cefrom, cedixen, and others. 

B) Seek the newly approved drug linezolid for possibility of vancomycin-resistant enterococci (VRE)... 

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