Energy-coupling mechanism

Early proposals concerning the mechanism of the energy-linked transhydrogenase reaction were based on the chemical hypothesis of oxidative phosphorylation [82] and visualized the involvement of high-energy intermediates of the type 1 X, NADH I, NADP I, etc. [29,46]. These proposals, however, just as the chemical hypothesis as a whole, had to be abandoned because of lack of experimental evidence. 

Certain similarities between mitochondrial transhydrogenase and ATPase have been pointed out in the past [91] and are further underlined by recent knowledge of the modes of action of the two enzymes. From the available data (cf.. Refs. 41-44) it appears clear that the thermodynamic effect of energy, i.e., A/Ih, involves a 

Another striking similarity between the transhydrogenase and ATPase is the kinetic effect of energy. Thus acts as an effector of the mitochondrial 

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Peck HD. 1968. Energy-coupling mechanisms in chemolithotrophic bacteria. Ann Rev Microbiol 22 489-518. 

C) Osmotic transformations suggest energy-coupling mechanism... 

Jockel, P., Schmid, M., Choinowski, T., and Dimroth, P. (2000) Essential role of tyrosine 229 of the oxaloacetate decorboxylase p-subunitin the energy coupling mechanism of the Na+ pump, Biochemistry, 39, 4320-4326. 

Cherepanov DA, Feniouk BA, Junge W, Mulkidjanian AY Low dielectric permittivity of water at the membrane interface Effect on the energy coupling mechanism in biological membranes. Biophys J 2003, 85(2) 1307—1316. 

Combustion d5mamics phenomena have important practical consequences and their prediction, alleviation, and reduction constitute technological challenges [10-12]. This requires an understanding of (1) the driving mechanisms that feed energy into the wave motion and (2) the acoustic coupling mechanisms that close the feedback loop. 

The mechanism of the coupling between ATP hydrolysis and Ca transport is determined by the spatial relationship of the phosphorylation and ATP binding domains of the Ca -ATPase to the Ca channel involved in the translocation of calcium. Two alternative coupling mechanisms have been proposed, based on two rather different hypothetical models of the structure of the Ca -ATPase. In the conformational coupling mechanism the energy transfer between ATP hydrolysis and transport involves a mechanical coupling over long distances between... 

Now, comparing 7Sf and /Sf ex, we observe also some splitting modifications. We may attribute them to some additional changes in the frequency gap. Indeed, as shown in Section V.B, the full treatment of the Fermi coupling mechanism leads to a displacement of the potential of the fast mode (both in energy and position) that does not appear within the exchange approximation. The fast mode then involves an effective frequency that differs from oo0, which leads to an effective gap which differs from (oo0 — 2oog). 

Specific receptors for siderophores and vitamin B12 have been identified in the OM of Gram-negative bacteria. The translocation of these ligands across the outer membrane follows an energy-dependent mechanism and also involves the TonB, ExbB, ExbD proteins anchored in the cytoplasmic membrane. Biochemical and genetic data indicate that these proteins form a functional unit (the Ton complex), which couples the outer membrane receptor-mediated... 

Tanford, C. (1983). Mechanism of free energy coupling in active transport, Ann. Rev. Biochem., 52, 379-409. 

Odom JM, Peck HD Jr. 1981. Hydrogen cycling as a general mechanism for energy coupling in the sulfate-reducing bacteria, Desulfovibrio sp. FEMS Microbiol Lett 12 47-50. 

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