Electrospinning fabricating tissue engineering

Khil MS, Bhattarai SR, KimHY,KimSZ and Lee KH, Novel fabricated matrix via electrospinning for tissue engineering , / Biomed. Mater. Res. Part B Appl. Biomater., 2005,72B, 117-124. 

An important commercial application of the nondegradable electrospun fibers is high-efficiency particulate absorption (HEPA) filters for air purification. In biomedical area, electrospinning is used to fabricate tissue engineering scaffolds to mimic ECM function, in which the cell response of the mat can be tuned by tuning fiber diameter and mesh size. 

Electrospinning of PHA is still relatively new in scaffold fabrication. To date, P(3HB) and P(3HB-co-3HV) are the most common microbial polyesters to be electrospun into tissue-engineering scaffolds. Suwantong et al. (2007) prepared ultrafine electrospun fiber mats of P(3HB) and P(3HB-co-3HV) as scaffolding materials for skin and nerve generation, hi their study, they evaluated the in vitro biocompatibility of these fibers using mouse fibroblasts and Schwann cells... 

There is currently a renewed interest in the use of electrospinning techniques for the fabrication of membranes. Chapter 8 reviews the use of this versatile technique for the production of nanofiber webs or membranes. The chemical and physical properties of nanofiber manbrane surfaces play an important role in their application to filtration, biomedical materials, tissue engineering scaffolds, drug delivery... 

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