Electron spin resonance studies agent

Li, A.S.W. and Chignell, C.F. (1987b) Spectroscopic studies of cutaneous photosensitizing agents. X. A spin-trapping and direct electron spin resonance study of the photochemical pathways of daunomycin and adriamycin, Photochem. Photobiol., 45, 565-570. 

Yoshikawa, T., Naito, Y., Tanigawa, T. and Kondo, M. (1993). Free radical scavei ng activity of the novel anti-ulcer agent rebamipide studied by electron spin resonance. Arzneim-Forsch. 43, 363-366. 

Thermolysis of aryl chloro diazirine (18) in the presence of acetone and a trapping agent such as A -phenylmaleimide gave rise to cycloadducts such as 41. The unstable adduct hydrolyzed during purification resulting in synthesis of bicyclic hemiacetals 42 and 43 as a mixture of endo and exo adducts in 37 and 8% yield, respectively. The exclusive generation of the singlet carbene was confirmed by low-temperature electron spin resonance (ESR) study of the irradiated diazirine. 

In past studies (3), Electron Spin Resonance, ESR, has been used to investigate bond rupture associated with stress-ozone degradation in unsaturated rubbers. It was believed that it might be enlightening to perform similar experiments on plastics ( 5, 8, 10, 11). In the study reported here the combined effects of environment (O3, N02 and S02) and sustained stress on the ultimate properties of Nylon 6 fibers are presented. These agents were found to have a profound effect on strength, toughness and the deformation-bond rupture kinetics. 

In certain systems ascorbic acid free radical on the 2- and 3-positions may be an intermediate in the antioxidant function, but it is a short-lived intermediate (18). An electron spin resonance flow system was used to study scavenging of a nitrosating agent by ascorbic acid, and a total spin free radical, which is the same as that produced by radiolytic oxidation (48), was determined (47). 

Many approaches have been used to study membrane structure electron microscopy of freeze-fractured and freeze-etched preparations, localization of antigens using ferritin-labelled antibodies, crossed immunoelectrophoresis, chemical probes and cross-linking agents, and instrumental techniques such as nuclear magnetic resonance and electron spin resonance spectroscopy. Their contribution to our present understanding of membrane anatomy has been reviewed by Salton and Owen [24]. 

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