Metabolism electrolyte

Another major function of the adrenal cortex is the regulation of water and electrolyte metabolism. The principal mineralocorticoid, aldosterone, can increase the rate of sodium reabsorption and potassium excretion severalfold. This will occur physiologically in response to sodium or volume depletion or both. The primary site of... 

T3. Tegelaers, W. H. H., and Tiddens, H. W., Nephrotic-glucosuric-aminoaciduric dwarfism and electrolyte metabolism. Helv. Paediat. Acta 10, 269-278 (1955). 

Douglas, VI.W. Ciba Foundation Symposium 1978, 34, 61. Brown, E.M. Mineral Electrolyte Metabolism 1962, HQ., 3. Peck, W.A. Klahr, S. "Advances in Cyclic Nucleotides Research" Raven Press New York, 1979 Vol 11, p 89. Heath, III, H. Endocrine Reviews 1980, 1, 319. 

Know the biosynthesis, functions, and chemical nature of steroid hormones. Be familiar with water and electrolyte metabolism and the control factors involved, and solve problems involving serum electrolytes. 

Schaefer L, Malchow M, Schaefer RM et al. (1996) Effects of parathyroid hormone on renal tubular proteinases. Miner Electrolyte Metabol 22 182-186 Shimizu T, Hata S, Kuroda T et al. (1999) Different roles of two types of endothelin receptors in partial ablation-induced chronic renal failure in rats. Eur J Pharmacol 381 39-49 Stockelman MG, Lorenz JN, Smith FN et al. (1998) Chronic renal failure in a mouse model of human adenine phos-phoribosyltransferase deficiency. Am J Physiol 275 Renal Physiol 44 F154-F163... 

Ascites and oedema are also found in severe hepatic diseases, pointing to serious disorders in the water and electrolyte metabolism. These complications are signs of decompensation in fiver cirrhosis or chronic liver insufficiency. At the same time, pleural effusion may also be evident. Cirrhosis-related pleural effusion without concomitant ascites has been described as a rarity. (see chapter 16)... 

Porter GA. Contrast-associated nephropathy presentation, pathophysiology and management. Mineral Electrolyte Metabolism 1994 20 232-243. 

Martinez-Maldonado M, Stravroulakl-Tsapar A,Tsaparas N. Renal effects of lithium administration In rats alterations In water and electrolyte metabolism and the response to vasopressin and cyclic adenosine monophosphate during prolonged administration. J Lab Clin Med 1975 86 445-461. 

Galla JN, Forrest JN, Hecht B, Kashgarian M, Hayslett JP. Effect of lithium on water and electrolyte metabolism. Yale J Biol Med 1975 48 305-314. 

Composite data from Muntwyler, E. (1968) Water and Electrolyte Metabolism and Acid-Base Balance, p. 14. Mosby, St. Louis, Missouri White, A., Handler, P, and Smith, E. L. (1973) Principles of Biochemistry, 5th ed., p. 802. McGraw-Hill, New York Long, C. (1961) Biochemist s Handbook, p. 670. Van Nostrand, Princeton, New Jersey. Reported ranges for some constituents are very wide. 

Eanestil DD, Moore ED. Compartmentation of body water. In Narins RG, ed. Maxwell and Kleeman s Huid and Electrolyte Metabolism, 5th ed. New York, McGraw-Hill, 1994 1-20. 

Drugs that affect renal function and electrolyte metabolism... 

R8. Robson, J. S., Influence of endocrine disease on the renal excretion of water. In "Symposium on Water Electrolyte Metabolism Elsevier, Amsterdam, 1960. 

Absence of gastrointestinal disturbances, usually observed at much lower salicylic acid doses, was again striking. With infusion therapy, the blood picture, kidney and liver functions, blood sugar, serum electrophoresis, electrolyte metabolism, ECG and rheumatic serology were evaluated. No pathological changes or abnormal reactions were found. Nor were there any cerebral, respiratory, or circulatory toxicities observed. 

Apart from tinnitus, sweating and transient nausea, no serious toxic disturbances were observed. Blood chemistry, kidney and liver functions, serum electrophoresis, and electrolyte metabolism revealed no pathological changes or abnormal clinico-chemical reactions. 

Jennee FA, Lee CR, Paschalis C, Hill SE, Bue-kinshaw L and Jennings G (1983) Electrolyte metabolism in patients with periodic affective disorders during treatment with rubidium. Psychopharmacology 81 301-309. 

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