Electrochemical diagnostic methods determination

In early 1983, Bioanalytical Systems introduced a new class of integrated processor-driven instrumentation based on a concept first developed by Faulkner and his co-workers [1] at the University of Illinois. This unit (Figs. 6.22 and 6.23) has evolved over the years and now includes a repertoire of some 35 electrochemical techniques, including the most popular large-amplitude (Chap. 3) and small-amplitude (Chap. 5) controlled-potential methods. The unit also is capable of determining electrocapillary curves and can automatically measure and compensate for solution resistance (R in Fig. 6.5). Thus in a single instrument it is possible to utilize virtually all of the diagnostic criteria introduced in Chapters 3 and 5 and also to explore quickly which technique is optimum for... 

Reference methods for blood gas and electrolyte determinations have been described in detail by the IFCC. A schematic diagram characteristic of a typical instrument is shown in Figure 27-4. Electrochemical principles and structural features of electrodes are discussed in Chapter 4. Prominent manufacturers of blood gas equipment include Roche Scientific Corp., Bayer Diagnostics, Instrumentation Laboratory, Nova Biomedical, and Radiometer America, Inc. Readers are referred to these manufacturers for details and operational features of specific instruments. 

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