Eczema intravenous

Synthetic glucocorticoids are prednisolone, prednisone, methylprednisolone, dexamethasone, betamethasone and triamcinolone (Table 13.2). Hydrocortisone is available as either succinate or phosphate salts for oral and intravenous administration. It is the drug of choice when a rapid effect is required, e.g. acute adrenal insufficiency, or as peri-operative replacement therapy. Prednisolone can also be given intravenously. It has about 0.8 of the mineralocorticoid activity of hydrocortisone. Prednisone is a prodrug that is converted to prednisolone in the body. For chronic therapy, synthetic steroids without mineralocorticoid activity are preferred, such as dexamethasone, betamethasone or triamcinalone. Beclo-metasone passes membranes poorly and is more active topically than when given orally. It is used as an aerosol for chronic rhinitis and asthma, and topically in severe eczema. Fludrocortisone is a synthetic halogenated derivate of cortisol that is used for its mineralocorticoid effect. 

Skin reactions to intravenous immunoglobulin are rare (52,93-95). Other reported reactions include urticaria, maculopapular rashes, petechiae, eczema, and erythema multiforme (31,96). 

DERMATOLOGICAL AGENT in a number of skin preparations, e.g. to treat eczema and psoriasis (as a hydrating agent). It can be given intravenously as a hypertonic dehydrating (osmotic) diuretic to reduce intracranial pressure in controlling cerebral oedema. 

The clinical use of heparin in inflammatory, allergic, and infectious diseases is reviewed. Intravenous heparin proved effective in eczemas, hay fever. 

Skin Cutaneous reactions that are associated with intravenous immunoglobulin include erythema at the injection site, rashes, urticaria [40 ], and eczema [43 ]. 

Skin Cutaneous reactions associated with intravenous immunoglobulin are uncommon, but include pruritus, non-specific eruptions, erythema, urticaria, eczema, pompholyx, pete-chiae, and skin hemorrhage [53, 54 , 55 , 57 , 59 ]. 

Immunologic A patient with delayed-type hypersensitivity to heparins was given danaparoid subcutaneously for thrombosis prophylaxis after orthopedic surgery and after the first few injections developed eczematous plaques followed by generalized eczema despite treatment with topical and oral glucocorticoids danaparoid was replaced by intravenous heparin, and there was rapid resolution of the skin lesions [130 ]. 

Lee KC, Ladizinski B. Dyshidrotic eczema following intravenous immunoglobulin treatment. CMAJ Can Med Assoc J August 6,... 

SHraishi T, Yamamoto T. Severe dyshidrotic eczema after intravenous immunoglobulin therapy for Kawasaki syndrome. Pediatr Dermatol 2013 May-Jun 30(3) e30-1. 

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