Ecological Structure Activity Relationships ECOSAR

The US EPA Ecological Structure Activity Relationships (ECOSAR ) Class Program estimates the aquatic toxicity of industrial chemicals, in particular... 

US Environmental Protection Agency (2011) Ecological Structure Activity Relationships (ECOSAR) http //www.epa. gov/oppt/newchems/tools /21ecosar.htm (last accessed 14 September 2011). 

Ecological Structure-Activity Relationships (ECOSAR) This model is used to predict aquatic toxicity, an increasingly important component of the EPA risk assessment program. The EPA has a large information database for chemicals that have been the subject of PMN, but for which the PMN was submitted as confidential business information (CBI). This represents just one example where relying on the model alone will not predict the EPA s response to the submission. 

United States Environmental Protection Agency (2011) Methodology document for the ecological Structure-Activity Relationship Model (ECOSAR) Class Program MS-Windows Version 1.1 Office of Pollution Prevention and Toxics, Washington, DC. http //www.epa.gov/ oppt/newchems/tools/ecosartechfinal.pdf. Accessed 09 Mar 2012... 

ERA ECOSAR, ecological structure activity relationships. http //www.epa.gov/opptintr/newchems/21ecosar.htm. 

Sources of information that can be accessed for evaluating products include the Hazardous Substances Data Base, which contains a summary of the fate of the substance in the environment and can be accessed via MEDLARS (Medical Literature Analysis and Retrieval System) [a.405], the EPA AQUIRE (Environmental Protection Agency-Aquatic Life) data base, which contains a listing of aquatic toxicity data for many industrial chemicals [a.406], Syracuse University s data base of fate studies [a.407], and quantitative structure-activity relationships (QSARs) such as the EPA programme ECOSAR (Ecological... 

---