DTI, Diffusion Tensor Imaging

DTI diffusion tensor imaging Fz/PCP Ffizzled/planar cell polarity... 

Diffusion tensor imaging (DTI) is a sophisticated form of diffusion imaging that is not yet routinely used in clinical stroke. However, it is becoming increasingly popular as a research tool (Sotak 2002), particularly in small lacunar stroke (Gillard et al. 2001 Lie et al. 2004) and in patients with ischemic leukoaraiosis (O Sullivan et al. 2001, 2004), and will, thus, be shortly described here. 

Diffusion tensor imaging (DTI) is a MRI method that allows examination of white matter integrity by measuring the directional diffusion of water. When there are no structural boundaries, water diffuses in all directions equally. When there are structural barriers, including myelin and cell membranes, diffusion tends... 

NAA in left FL of patients NAA reduction correlated with severity of negative symptoms and poorer Wisconsin Card Sort performance 4 NAA and diffusion tensor imaging (DTI) anisotropy in medial temporal WM in patients no differences in DLPFC or occipital WM... 

Tang CY, Friedman J, Shungu D, Chang L, Ernst T, et al. 2007. Correlations between diffusion tensor imaging (dti) and magnetic resonance spectroscopy (lh mrs) in schizophrenic patients and normal controls. BMC Psychiatry 7 25. 

Honea R, Crow TJ, Passingham D, Mackay CE. Regional deficits in brain volume in schizophrenia a meta-analysis of voxel-based morphometry studies. Am. J. Psychiatry 2005 162 2233-2245. Kubicki M, Westin CF, McCarley RW, Shenton ME. The application of DTI to investigate white matter abnormalities in schizophrenia. Ann. N. Y. Acad. Sci. 2005 1064 134-148. White T, Kendi AT, Lehericy S, Kendi M, Karatekin C, Guimaraes A, Davenport N, Schulz SC, Lim KO. Disruption of hippocampal connectivity in children and adolescents with schizophrenia-a voxel-based diffusion tensor imaging study. Schizophr. Res. 2007 90 302-307. 

Multiple metrics can be calculated from diffusion tensor imaging (DTI) data, typically mean cUffusivity (D ) and fractional... 

The collagen fiber alignment angles, obtained from polarized light microscopy (PLM) and diffusion-tensor imaging (DTI), were statistically compared in five samples of the bovine articular cartilage from five different... 

Diffusion tensor imaging (DTI) and quantitative T-2 MRI were used to characterize ex vivo the white matter damage at 3 and 8 weeks following dorsal column transection (DC Tx) injury at the cervical level C5 of rat spinal cords. " This study demonstrates that quantitative MRI can accurately characterize white matter damage in DC Tx model of injury in rat spinal cord. 

---