Drugs metabolism and transport

Meisel C, Roots I, Cascorbi I, Brink-mann U, Brockmoller J. How to manage individualized drug therapy application of pharmacogenetic knowledge of drug metabolism and transport. Clin Chem Lab Med 2000 38 869-876. 

Nolin TD, Erye RF, Matzke GR (2003) Hepatic drug metabolism and transport in patients with kidney disease. Am J Kidney Dis 42(5) 906-925... 

Harris RZ, Jang GR, Tsunoda S. Dietary effects on drug metabolism and transport. Clin Pharmacokinet 2003 42(13) 1071-1088. 

The extent to which the cell line is appropriate for drug metabolism and transport studies. If drug bidirectional transport studies are to be performed, the cell line needs to form monolayers with tight cell-cell junctions. If cell-cell junctions are loose, background (or nontransporter-dependent) paracellular drug transport... 

Lash, L. H. (Ed.) Drug Metabolism and Transport. Humana Press Totowa, NJ, 2005. 

Prior to start multiple formulation efforts and work-intensive in vivo formulation optimization experiments, an assessment should be made on whether drug metabolism and transport are relevant pharmacokinetic driving factors for the substance to be formulated. 

Lash, L. H. (2005). Drug metabolism and transport Molecular methods and mechanisms. Totowa, N.J. Humana Press. 

Svensson, C. K., Sc Hein, D. W. (2005). Phenotypic and genotypic characterization of N-acetylation. In L. H. Lash (Ed.), Drug Metabolism and Transport Molecular Methods and Mechanisms (pp. 173—196). Totowa, Humana Press. 

Drug-Drug Interactions with an Emphasis on Drug Metabolism and Transport... 

---