Drug reactions cough

Bronchospasm with clarithromycin occurred in a 44-year-old woman who had no history of respiratory allergies but had had adverse drug reactions to general and regional anesthetics and to ceftriaxone (14). After the administration of a quarter of the therapeutic dose the patient had dyspnea, cough, and bronchospasm throughout the lung. 

Suspected adverse drug reactions, e.g. dry cough is a well-known side-effect of angiotensinconverting enzyme inhibitors... 

Adverse drug reactions drugs that can produce cough as a side-effect include angiotensin-converting enzyme inhibitors, non-steroidal anti-inflammatory drugs and beta-blockers. 

It has been suggested that ACE inhibitors that contain a phosphonate group may be more likely to cause cough. However, the comparison of enalapril, lisinopril, ramipril, and fosinopril on which this statement was based was very small n = 120) and unlikely to be able to measure differences in the incidences of adverse drug reactions [35 ]. 

The problems of multiple prescribing in the elderly have been discussed in the context of a case of enalapril-associated dry cough misdiagnosed as pneumonia [34" ]. The prescribed antibiotics caused pseudomembranous colitis and an opioid-based syrup contributed to delirium. The authors drew attention to the effect of the prescribing cascade that can occur following the failure to identify an adverse drug reaction. 

Use of codeine may result in respiratory depression, euphoria, light-headedness, sedation, nausea, vomiting, and hypersensitivity reactions. The more common adverse reactions associated with the antitussives are listed in the Summary Drug Table Antitussive, Mucolytic, and Expectorant Drugs. When used as directed, nonprescription cough medicines containing two or more ingredients have few adverse reactions. However, those that contain an antihistamine may cause drowsiness. 

ADMINISTERING ACE INHIBITORS. The nurse administers captopril and moexipril 1 hour before or 2 hours after meals to enhance absorption. Some patients taking an ACE inhibitor experience a dry cough that does not subside until the drug therapy is discontinued. This reaction may need to be tolerated. If the cough becomes too bothersome, the primary care provider may discontinue use of the drug. 

Differences in receptor sensitivity have been offered to explain the spectrum of unexpected drug responses observed in children. Neonates and young children are at increased risk to experience paradoxical CNS stimulation following antihistamine administration. Symptoms observed in pediatric cases of acute overdose include hallucinations, excitation, and seizures. A physiological explanation for this reaction has not been identified. Antihistamines should not be included in over-the-counter (OTC) cough and cold products recommended for infants and young children. 

Hydrocodone is an opium analgesic (pain reliever) and antitussive (cough suppressant). It is related in structure to other alkaloids used as drugs, such as morphine and codeine (see Section 8). It increased 20% in number of prescriptions for one year. Its synthesis from codeine is by simple reactions. 

A. Although many drugs can evoke a reaction such as a rash, a rash and a dry cough are well-recognized side effects of angiotensin converting enzyme... 

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