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Drug-induced QT interval prolongation

Malik, M. and Camm, A.J. (2001) Evaluation of drug-induced QT interval prolongation implications for drug approval and labelling. Drug Safety, 24, 323-351. [Pg.81]

Malik, M. (2001) Problems of heart rate correction in assessment of drug-induced QT interval prolongation. Journal of Cardiovascular Electrophysiology, 12, 411—420. [Pg.83]

Fermini, B. and Fossa, A.A. (2003) The impact of drug-induced QT interval prolongation on drug discovery and development. Nature Reviews. Drug Discovery, 2, 439—447. [Pg.123]

Ando, K., Ikeda, H., Yamamoto, K., and Sagami, F., Dose (concentration)-response analysis of drug-induced QT interval prolongation in conscious monkeys (JPMA QT prodact), /. Pharmacol. Toxicol. Methods, 49, 220, 2004. [Pg.287]

Pollard, C.E., Valentin, J.P. and Hammond, TG. (2009) Strategies to reduce the risk of drug-induced QT interval prolongation a pharmaceutical company perspective. British Journal of Pharmacology, in press. [Pg.406]

Dumotier, B.M., Deurinck, M., Yang, Y, Traebert, M. and Suter, W. (2008) Relevance ofiuvitroSCREENlTresultsfor drug-induced QT interval prolongation... [Pg.411]

Relationships between the whimsically named human ether-a-go-go related gene (hERG), drug-induced QT interval prolongation, and the torsades de... [Pg.316]

QTc values are used in analysis of potential drug-induced QT interval prolongation, where the c stands for corrected for heart rate. Many correction factors have been developed to address this issue (see Camm et al. 2004). The more commonly used correction factors, QTcB (Bazett s correction) and QTcE (Eridericia s correction)... [Pg.145]


See other pages where Drug-induced QT interval prolongation is mentioned: [Pg.762]    [Pg.492]    [Pg.283]    [Pg.354]    [Pg.83]    [Pg.477]    [Pg.485]    [Pg.485]    [Pg.313]    [Pg.158]    [Pg.60]    [Pg.68]    [Pg.110]    [Pg.111]    [Pg.140]    [Pg.158]    [Pg.164]    [Pg.201]    [Pg.465]    [Pg.466]   
See also in sourсe #XX -- [ Pg.485 ]




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Prolonged QT interval

QT prolongation

QT prolongers

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