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Drug-induced kidney injury

Dieterle F, Perentes E, Cordier A, Roth DR, Verdes P, Grenet O, Pantano S, Moulin P, Wahl D, Mahl A, End P, Staedtler F, Legay F, Carl K, Laurie D, Chibout SD, Vonderscher J, Maurer G (2010) Urinary clusterin, cys-tatin C, beta2-microglobulin and total protein as markers to detect drug-induced kidney injury. Nat Biotechnol 28(5) 463-469. doi 10.1038/nbt. 1622... [Pg.473]

Rouse R, Zhang J, Stewart SR, Rosenzweig BA, Espandiari P and Sadrieh NK (2011) Comparative profile of commercially available urinary biomarkers in preclinical drug-induced kidney injury and recovery in rats. Kidney Int. 79(11) 1186-97. [Pg.10]

ASSESSING AND PREDICTING DRUG-INDUCED KIDNEY INJURY, FUNCTIONAL CHANGE, AND SAFETY IN PRECLINICAL STUDIES IN RATS... [Pg.431]

EMA. (2014) Letter of Support for PSTC Translational Drug-Induced Kidney Injury (DIKI) Biomarkers. Available at www.ema.europa.eu/docs/en GB/document library/ Other/2014/ll/WC500177133.pdf (accessed October 20,2015). [Pg.439]

McDuffie JE, Adler S, Philhps JA, Sonee M, Lynch K, Gautier J-C, and Burt D. Nonrodents Can Be Monitored, Too... Characterization of Novel Biomarkers of Drug-Induced Kidney Injury (DIKI) in Rats, Canines, Nonhuman Primates, and Humans. The Toxicologist. 80 Minute Workshop. Informational Session. 310(1) 98, 2014. [Pg.445]

TRADITIONAL KIDNEY SAFETY PROTEIN BIOMARKERS AND NEXT-GENERATION DRUG-INDUCED KIDNEY INJURY BIOMARKERS IN NONHUMAN PRIMATES... [Pg.446]

Guha M., Heier A., Price S., Bielenstein M., Caccese R. G., Heathcote D. 1., Simpson T. R., Stong D. B., and Bodes E. Assessment of biomarkers of drug-induced kidney injury in cynomolgus monkeys treated with a triple reuptake inhibitor. Toxicological Sciences-, 120(2) 269-283 (2011). [Pg.447]

FIGURE 28.2 Select qualified and unqualified biomarkers used when monitoring for drug-induced kidney injury to specific nephron segments in rats. Adapted from Bonventre et al. (2010). [Pg.568]

Introduction Impact of Drug-Induced Kidney Injury on Drug Development... [Pg.325]

See other pages where Drug-induced kidney injury is mentioned: [Pg.431]    [Pg.443]    [Pg.444]    [Pg.444]    [Pg.446]    [Pg.490]    [Pg.503]    [Pg.323]    [Pg.324]    [Pg.324]    [Pg.347]   


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