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Drug development simulation

Cavoy E., Deltent M. E, Lehoucq S., Miggiano D. (1997) Laboratory-Developed Simulated Moving Bed for Chiral Drug Separations. Design of the System and Separation of Tramadol Enantiomers, J. Chrotnatogr. A 769 49-57. [Pg.250]

Schjpdt-Eriksen J, Clausen J. Optimization and simulation in drug development—review and analysis http //www.imm.dtu.dk/pubdb/views/edoc download.php/2834/ps/imm2834.ps... [Pg.273]

Bonate PL. Clinical trial simulation in drug development. Pharm Res 2000 17 252-6. [Pg.525]

Holford NHG, Hale M, Ko HC, Steimer J-L, Sheiner LB, Peck CC et al. Simulation in Drug Development Good Practices. Draft Publication of the Center for Drug Development Science (CDDS) Draft version 1.0, July 23, 1999, http //cdds.georgetown.edu/research/sddgp723.html (accessed October 1, 2005)... [Pg.526]

Gieschke, R. and Steimer, J.L., Pharmacometrics modelling and simulation tools to improve decision making in clinical drug development, Eur.. Drug Metab. Pharmacokinet., 25, 49-58, 2000. [Pg.372]

Establishing a Dynamic Model Simulation Framework for the Drug Development Process... [Pg.641]

Portion of the drug development framework populated with sample simulation agents. [Pg.646]

The basic stock/flow structure and the associated simulation model of pharmaceutical pipeline management provide a useful framework to analyze basic drug development... [Pg.651]

Fleury, A. and Reddy, M. (2007) Challenges and opportunities with modelling and simulation in drug discovery and drug development. Xenobiotica, TTl, 1295-1310. [Pg.238]

II. Product Summaries Simulations Plus develops simulation and predictive modeling software for in silico compound screening and for preclinical and clinical drug development in the area of Absorption, Distribution, Metabolism, Excretion and Toxicity (ADMET). The available applications include GastroPlus, ADMET Predictor, ADMET Modeler, DDDPlus, and MembranePlus. [Pg.229]

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Simulations in Clinical Drug Development Practical Examples

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