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Drug design synthetic peptides

Mimicking the secondary structure of peptides has become one of the most important tools for rational drug design (44-47). These methods induce the synthetic analog to adopt a set of target conformations, which are designed to mimic the bioactive conformation predicted in the native substrate from biophysical techniques. Molecular surrogates... [Pg.639]

Li W, Nicol F, Szoka F C, Jr (2004). GALA A designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery. Adv. Drug Deli. Rev. 56 967-985. [Pg.292]

V. J. Hruby, W. Kazmierski, A. M. Kawasaki, and T. O. Matsunaga, in Peptide Pharmaceuticals, D. J. Ward, Ed., Elsevier, New York, 1991, pp. 135-184. Synthetic Chemistry and the Design of Peptide-Based Drugs. M. D. Taylor, Peptide-Based Drug Design Controlling Transport and Metabolism, American Chemical Society, Washington, DC, 1995. [Pg.67]

See other pages where Drug design synthetic peptides is mentioned: [Pg.9]    [Pg.4]    [Pg.441]    [Pg.34]    [Pg.182]    [Pg.263]    [Pg.117]    [Pg.658]    [Pg.44]    [Pg.18]    [Pg.250]    [Pg.452]    [Pg.559]    [Pg.560]    [Pg.574]    [Pg.584]    [Pg.591]    [Pg.619]    [Pg.1269]    [Pg.263]    [Pg.311]    [Pg.15]    [Pg.153]    [Pg.1325]    [Pg.746]    [Pg.98]    [Pg.46]    [Pg.22]    [Pg.285]    [Pg.327]    [Pg.124]    [Pg.98]    [Pg.818]    [Pg.123]    [Pg.493]    [Pg.657]    [Pg.840]    [Pg.2]    [Pg.27]    [Pg.16]    [Pg.17]    [Pg.239]    [Pg.425]    [Pg.503]    [Pg.802]   
See also in sourсe #XX -- [ Pg.178 ]



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