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Peptide based drug design

Clearly, identification of resistance mechanisms and of potential intracellular targets all lead to information which would be very useful for the development of novel anti-infective drugs by peptide-based design, once the structure of these targets is known. In addition, identification of transport proteins that may... [Pg.162]

Yee, S. and G. L. Amidon. Oral absorption of angiotensin-converting enzyme inhibitors and peptide prodrugs. In Peptide-based Drug Design. G. L. Amidon (ed), American Chemistry Society, Washington DC 1995, 137-147. [Pg.271]

In this volume many investigators report on their own studies in conformationally directed drug design. The common theme of all the chapters is the importance of the conformational structure of peptide and nucleic acid in the design of drugs that are either peptide- or nucleic-acid-based or that interact with peptides or nucleic acids. We anticipate that at the present rate of progress significant therapeutic advances will result from... [Pg.1]

II. Peptide Ligand Lead Discovery and Structure-Based Drug Design... [Pg.569]

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See also in sourсe #XX -- [ Pg.2 , Pg.3 , Pg.4 , Pg.5 , Pg.103 , Pg.108 ]



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