Drug delivery systems MEMS based

Reservoir-Based MEMS Drug Delivery System... 

Reservoir-Based MEMS Drug Delivery System, Fig. 1 Dmg conccaitration as a function of time. Singledose profile depicts a typical dmg concentration profile using eonventional dmg delivery routes. Controlled-release profiles depict the dmg concentration profile fiom a etmtrolled-release drag delivery system... 

Reservoir-Based MEMS Drug Delivery System, Fig. 3 An electrocliemically actuated microcliip, (A) a cutaway portion of a microcliip (17 x 17 mm x 310 pm) containing reservoirs filled with the chemical to be released. Release from a particular reservoir is initiated by applying an electric potential between the gold anode... 

Reservoir-Based MEMS Drug Delivery System, Fig. 4 A magnetically controlled MEMS device for on-demand and controlled drug delivery. Uprai application of a magnetic field ( 250 mT), the membrane... 

Gottsche T (2007) Highly integrated oral drug delivery system with valve based on electro-active-polymer. hr IEEE MEMS 2007, Kobe, pp 461 64 Heywang G, Jonas F (1992) Poly (alkylenedioxythiophene)s - new, very stable conducting polymers. Adv Mater 4 116-118... 

Yuzhakov et al. [93] describe the production of an intracutaneous microneedle array and provide an account of its use (microfabrication technology). Various embodiments of this invention can include a microneedle array as part of a closed loop system smart patch to control drug delivery based on feedback information from analysis of body fluids. Dual purpose hollow microneedle systems for transdermal delivery and extraction which can be coupled with electrotransport methods are also described by Trautman et al. [91] and Allen et al. [100]. These mechanical microdevices which interface with electronics in order to achieve a programmed or controlled drug release are referred to as microelectromechanical systems (MEMS) devices. 

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