Dose-response tests probit analysis

Statistical methods frequently employed in effluent toxicity evaluations include point estimation technique such as probit analysis, and hypothesis testing like Dunnett s analysis of variance (anova). Point estimation technique enables the investigator to derive a quantitative dose-response relationship. This method has been generally applied to statistical analyses of acute effluent monitoring data. 

Sensitisation. The observation from early studies that individuals who had been previously exposed to SM were more sensitive than naive individuals is supported by comparisons using the dose response of naive individuals in the mass sensitivity trials described above and the dose response curve for subjects previously burned by SM (Figure 5.6). The EDjo is significantly lower in previously burned subjects than in naive subjects (p < 0.001, F-test) and the probit slope is significantly shallower p < 0.001, analysis of variance on regression analysis). 

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