DNA device

One of the challenges of practical DNA devices is to find the right balance between a high surface density of DNA molecules, which is expected to increase the number of molecular recognition events per unit area of the device, and a loose molecular network, which is expected to increase the... 

The DNA devices (set 2) give the expected blue emission at 448 nm. The device with the conventional Mg Ag cathode exhibits poor electrical and optical characteristics, in which only a light output of 75 cd/m2 and a current density of 70 mA/... 

In addition to conventional applications in conducting polymers and electrooptical devices, a number of recent novel applications have emerged. Switching of DNA electron transfer upon single-strand/double-strand hybridization fonns the basis for a new medical biosensor teclmology. Since the number of base pairs of length 20... 

The first application is related to tire molecular interaction between surface-liirked DNA and pollutants or dmgs, in order to develop a simple device for rapid screening of toxic compounds or better to try to quantify the genotoxicity of a specific sample. 

A gene gun is a device to introduce DNA into cells in vivo. The DNA is attached to gold particles, which are introduced under high velocity into the target tissue. 

Construction of the DNA chip (Nicolini 1996) requires a single-helix DNA immobilized at the surface of the device and sensitive to the binding of the complementary strand. 

The use of DNA hybridization just described opens up a novel, uncomplicated, yet powerful strategy for supramolecular synthesis Many different devices are connected to a distinct sequence codon and are subsequently organized on a suitable template strand. The utilization of appropriate nucleic acid scaffolds should even allow the fabrication of highly complex supramolecular structures by means of a modular construction kit. For approximately 20 years, the work of Seeman and coworkers [8,27] have been engaged in the rational construction of ID, 2D, and 3D DNA frameworks. They use branched DNA... 

Recent advances of the Seeman group led to the construction of a nanomechanical device from DNA [89]. In this molecular apparatus, the ion-dependent transition of B-DNA into the Z-conformation is used to alter the distance between two DNA DX domains attached to the switchable double helix. Atomic displacements of about 2-6 nm were attained. Ionic switching of nanoparticles by means of DNA supercoiling has also been reported [53]. Additional advances regarding the use of DNA is nanomechanical devices have been reported by Fritz et al., who showed that an array of cantilevers can be used to... 

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