DL-alanine, N-

SYNS DL-ALANINE, N-(2,6-DIMETHAXPHENYL)-N-(METHOXYACETYL)-, METHYL ESTER (SCI) APRON... 

DL-Alanine, N-benzoyl-N-(3-chloro-4-fluorophenyl)-, 1-methylethyl ester. See Flamprop-isopropyl... 

DL-Alanine, N-(2,6-dimethylphenyl)-N-(methoxyacetyl)-, methyl ester. See Metalaxyl P-Alanine, N-dodecyl-, compd. with 2,2 -iminobis [ethanol]. See DEA-lauraminopropionate... 

Synonyms DL-Alanine, N-benzoyl-N-(3-chloro-4-fluorophenyl)-, 1-methylethyl ester N-Benzoyl-N-(3-chloro-4-fluorophenyl)-DL-alanine 1-methylethyl ester Flufenprop-isopropyl Isopropyl N-benzoyl-N-(3-chloro-4-fluorophenyl)-2-aminopropionate Isopropyl ( )-2-(N-(3-chloro-4-fluorophenyl) benzamido) propionate... 

Treatment of Namino acids (N-Q>etho-DL-phenylalanine, N-Cbzo-DL-phenylalanine, N-Cbetho-DL-alanine, N-Q>zo-DL-alanine, N-Cbetho-DL-valine, N-... 

Acetyl-DL-alanine-N-methylamide, 40B, 438 -Acetyl-L-alanine-N-methylamide, 40B, 438 -Alanyl-L-alanine, 37B, 267 -Alanyl-L-serine, 44B, 433... 

Kurzlich teilten Matsuura et al. (232) die Bildung von optisch aktivem Poly-a-alanin durch stereospezifische Polymerisation von N-Carboxy-DL-alanin-anhydrid mit. 

The process of racemization is important in the survival and growth of living cells and is catalyzed by a group of enzymes called racemases. Alanine racemase. for example, is able to convert n-alanine to DL-alanine if a suitable alpha keto acid is also present. In this reaction the asymmetry of the alpha-carbon atom of alanine is lost as the amino acid is converted to the keto acid and back. This process is analogous to the well-known process of transamination in which racemization seldom occurs. 

Azidoacetyl-dl-alanine, CH,.CO.N(N,).CH(CH,). COOH, mw 172.15, N32.55%. Long fine ndls, mp 101°. Was prepd by Freudenberg Keller from dl-alanin by a procedure described in Ref 2. In the course of prepn of this compd an intermediate, Azidoacetyl-dl-alanine chloride was obtained. This chloride could not be purified because it decompd explosively at ca 30°... 

A 5 L, 3-neck round bottom flask equipped with a mechanical stirrer was charged with the N-acetyl-3-(4-thiazolyl)-DL-alanine ethyl ester (210.0 g, 0.87 mol), distilled water (1.6 L), and 1 M aqueous KCI (0.8 L). The homogeneous solution was adjusted to pH 7.0 with 0.1 M NaOH and then was treated with Subtilisin Carlsberg (1.8 g) dissolved in 0.1 M aqueous KCI (25 ml). The reaction mixture was stirred at room temperature with 1.0 M NaOH added as required to maintain the pH at 6.25-7.25. After 4 h, 430 ml of base had been consumed and the reaction was judged to be complete. The reaction mixture was then extracted with chloroform (4x1.5 L), the aqueous phase was carefully acidified to pH 4 with 2 M HCI and then was concentrated under reduced pressure. Residual water was removed by consecutive evaporation... 

N-( 2,6-dimethylpheny1)—N—(2-methoxyacety1)-DL-alanine, methyl ester (metalaxyl, Ridomil Ciba-Geigy)... 

N-(2,6-DIMETHYLPHENYL)-N-(METHOXYACETYL)-DL-ALANINE METHYL ESTER see MDMIOO N,N-DIMETHYL-3((1-PHENYLMETHYL)-1H-INDAZOL-3-YL)OXY-l-PROPAN AMINE HYDROCHLORIDE see BBW500 N-(2,6-DIMETHYLPHENYL)-l-METHYL-2-... 

Metalaxyl or methyl-N-(methoxyacyl)-N-(2,6-xylyl)-DL-alaninate Acylalanine Inhibits protein synthesis in fungi, systemic with protective action Control of air- and soil-bome diseases on crops 11-29... 

The synthetic polypeptide most completely studied in the solid state by optical rotation is poly-n-alanine, which Elliott et al. (1957b, 1958) treat as though it were an L-polypeptide with opposite helical sense in order to make straightforward comparison of the results with other studies. The 6o for the pure L-polymer is —475, and for two helical DL-copolymers, —500 and —505 extrapolated values for the meso-polypeptide lead to a fio of — 560. These compare favorably with Pasman s result of about —425 in 30% dichloroacetic acid in chloroform, a solvent in which the conformation is helical (I asman, 1961a). The [m ] values were found to be less than those obtained for solution, a result probably attributable to environmental changes, yet of meso-poly-DL-alanine is -f 70° at 578 m/u, which is... 

ClOH1003 m-methoxycinnamic acid, predominantly trans 6099-04-3 44.33 1.1531 2 19326 C10H11NO3 N-benzoyl-DL-alanine 1205-02-3 25.00 TT995 2... 

Resolution of DL-alanine (1) is accomplished by heating the N-acetyl derivative (2) in weakly alkaline solution with acylase, a proteinoid preparation from porcine kidney containing an enzyme that promotes rapid hydrolysis of N-acyl derivatives of natural L-amino acids but acts only immeasurably slowly on the unnatural o-isomers. N-Acetyl-DL-alanine (2) can thus be converted into a mixture of l-( + )-alanine (3) and N-acetyl-o-alanine (4). The mixture is easily separable into the components, because the free amino acid (3) is insoluble in ethanol and the N-acetyl derivative (4) is readily soluble in this solvent. Note that, in contrast to the weakly levorotatory o-( - )-alanine (a 14.4°), its acetyl derivative is strongly dextrorotatory. 

The melting point of N-acetyl-DL-alanine is 137°C and that of N-acetyl-D-alanine is 125°C. What would you expect the melting point of N-acetyl-L-alanine to be, or is this impossible to predict ... 

L-proline NCA is comparatively reactive. In part this may arise from strain in the molecule. However, the fused rings confer a saucer-like shape on the molecule and attack at C5 from the convex side should be relatively free from obstruction by substituents on the ring nitrogen and C4. This is probably the explanation of the comparatively fast reaction of L-proline NCA with Al-isopropylglycine dimethylamide (R4 = iPr), of which the rate coefficient is approximately 6000 times that of the corresponding reaction with N-methyl-DL-alanine NCA (R, = R3 = Me, R2 = H). 

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