Diversa Corporation

Justin Stege (Diversa Corporation) discussed the molecular evolution of enzymes for particular pathways, with a focus on the modification of oil composition. Oleochemical applications for such enzymes include applications as biocatalysts for fatty acid modifications. In a program to integrate production and processing, such enzymes can be used to modify the fatty acid content of vegetable oils in planta. Results show that expressing such new enzymes in oilseed crops has resulted in altered oil composition, and that the features may be used to better design plant-based oils for use as biofuels and as improved renewable feedstocks. 

Current affiliation Diversa Corporation, San Diego, California, U.S.A. 

We end this chapter with two much simpler reactions - a couple of desymmetrisations - each special in their own way. The hrst is amazingly efficient, using a lipase/esterase from a thermophilic organism supplied as a recombinant protein by the Diversa corporation. The symmetrical Diels-Alder adduct 231 is rapidly and perfectly desymmetrised to the monoacid61 232 at 70 °C. 

Diversa Diversa Corporation 4955 Directors Place San Diego, CA 92121-1609 USA Tel. +1 (858) 526-5000 Fax +1 (858)526-5551 Email information diversa.com http //www.diversa.com Discovery and development of industrial enzymes. No general biocatalyst portfolio. 

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