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Diseases predisposition

Swift, M., J. Cohen, and R. Pinkham. A maximum-likelihood method for estimating the disease predisposition of heterozygotes. Am. j. Hum. Genet. 26 304-317, 1974. [Pg.289]

The knowledge of the 3.2 biUion base pair human sequence information and information on oiu genetic diversity are milestones in oiu imderstanding of the contribution of genes to many complex problems such as disease predisposition and diversity of drug response by different patients. The manifestations of genetic diversity within the human genome are mostly SNPs, RFLPs (which can be... [Pg.63]

The strategies for discovering SNPs are either direct or indirect approaches. For a direct approach, certain regions of the genome, e.g. genes which may be interesting disease predisposition candidates, are chosen and screened thoroughly... [Pg.64]

Among the other potentials for the role of pharmacogenomics in the future of medicine, one could list customized therapy, screening for disease predisposition, customized preventative care, and improved extrapolation of drugs from adults to children. Pharmacogenomics could also be applied to nonhuman organisms, for example, to bacteria for identifying the correct antibiotic development [11]. [Pg.326]


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See also in sourсe #XX -- [ Pg.27 ]




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Predisposition

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