1.3- dioxo-l,3-diphenyl

Dioxo-l,3-diphenyl-propan891 929,939,1424,2275 3-Oxo-butansaure-ethylester891,928 - 931 939,1271 3-Oxo-3-phenyl-propansaure-ethylester891,939,1271... 

Pentandion ergibt bessere Ausbeuten als 1,3-Dioxo-l,3-diphenyl-propan. 

Nur eine Carbonyl-Gruppe wird bei der Hydrodimerisierung von 1,3-Dioxo- 1,3-diphenyl-propan an Quecksilber reduziert [90% d.Th. 1,6-Dioxo-l,6-diphenyl-hexandiol-(3,4)]9-, analog verhalt sich 3,5-Dioxo-l,l-dimethyl-cyclohexan (Dimedon)10 ... 

Dioxo-l,3-diphenyl-4ff,10/7-[l]benzothieno[5,6-6][2]benzotellurophene Several g of powdered tellurium are dissolved in aqua regia, the solution is heated until all nitrogen oxides have been expelled, and is then diluted with water. A solution of sodium hydrogen sulfite is added to precipitate amorphous tellurium. The tellurium is filtered off, washed with water until the washings arc neutral, and then several times with ethanol. 50 ml of xylene are placed in a nitrogen-flushed, 250 ml flask fitted with a reflux condenser. 638 mg (5 mmol) of the moist, amorphous tellurium and 502 mg (0.5 mmol) of the rhodium metallocycle are added. The mixture is refluxed under nitrogen for 8 h while a spatula tip of tellurium is added every 2 h. The mixture is then filtered, and the filter is placed on a silica gel column which is eluted with 9/1 benzene/petroleum ether. The second yellow band is collected, the solvent is evaporated, and the residue is crystallized from benzene/ethanol yield 100 mg (38%) m.p. 248°. 

Chemical Name 4-butyl-1,2-diphenyl-3,5-pyrazolidinedione Common Name 3,5-dioxo-l, 2-diphenyl-4-n-butylpyrazolidine Structural Formula ... 

Y2 receptors are characterised by an order of potency of NPY PYY > C-terminal fragment [Pro34]-substituted analogue > PP. BIIE 0246 ((S -iV2- 1 -[2-[4-[(i ,5)-5,11 -dihydro-6(6h)-oxodibenz[b,e]azepin-l 1 -yl]-l-piperazinyl]-2-oxoethyl]cyclopentyl]acetyl]-iV -[2-[l, 2-di-hydro-3,5-(4H)-dioxo-l, 2-diphenyl-3H-l, 2,4-ttiazol-4-yl]ethyl]-argininamide) is a Y2-selective antagonist with an affinity of 3 nM. 

In AcetonitrilundTctraathylammoniumperchlorat als Leitsalz erhalt manbei —2 V an Quecksilber aus l,5-Dioxo-l,5-diphenyl-pentan 1,2-Dihydroxy-1,2-diphenyl-cyclopen-tan (76% d.Th.)2, vgI"3 und aus l,6-Dioxo-l,6-bis-[4-hydroxy-phenyl]-hexan /,2-Dihydroxy- 1,2-bis- 4-hydroxy-phenyl]-cyclohexan3 ... 

Diphenyl- -butylester E2, 270 Diphenyl- -tert.-butylester XII/1, 284 Diphenyl- -[a-(3,5-dioxo-l,2-diphenyl-pyrazolidin-4-yl)-benzylester] E2, 274 Diphenyl- -(2,5-dioxo-hexylester) E2, 274 Diphenyl- -f -(l,3-dioxo-2-indanyl)-benzylester] E2,274... 

DIGIBUTINA DIOSSIDONE 3,5-DIOXO-l,2-DIPHENYL-4-N-BU1TLPYRAZOUDENE DIOZOL DIPHEBUZOL DIPHENYLBUTAZONE 1,2-DIPHENYI 4-BUTYL-3,5-DIOXOPYRAZOLIDINE ELMEDAL EQUI BUTE ERIBUTAZONE ESTEVE... 

The following alkoxypyrazines have been prepared from the corresponding dichloropyrazines and alkoxide ions 2,3-dimethoxy-5,6-dimethyl(and diphenyl) (797) 2,3-dibenzyloxy (sodium benzyl oxide in benzyl alcohol at reflux for 24 hours (883)] [but 23-dichloropyrazine with sodium hydride and benzyl alcohol in xylene gave l,4-dibenzyl-2,3-dioxo-l,2,3,4-tetrahydropyrazine)(988)] 2-chloro-5-methoxy (838) 2,5-diethoxy-3,6-dimethyl (872) 2methanolic sodium methoxide refluxed for 2 h) 2,5-dimethoxy-3-phenyl (817) 2-chloro-5-methoxy(and ethoxy)-3,6-diphenyl (817) 2,5-dimethoxy-3,6-dimethyl (and diisopropyl) (844) 2,5-dimethoxy-3-isopropyl-6-methyl (methanolic potassium methoxide at reflux for 6 days) (844) 2(5)-s-butyl-3-chloro-6-ethoxy-5(2)-isobutyl (93) 2-chloro-6-methoxy (838, 883) 2,6-dimethoxy (reflux for 8h) (832) 2,6-diethoxy (reflux for 14 h) (883) 2-benzyloxy-6-chloro (1 equiv. of sodium hydride and benzyl alcohol in benzene at reflux) (832) 2,6-dibenzyloxy (5 equiv. of sodium benzyloxide in benzene at reflux gave 70%) (832) and 3,5-dimethoxy-2-methyl (535). 

Dlmethyl-4,6-dioxo-l,3-dioxane-5-ylidene)-2,6-diphenyl-4//-tellurin 1.44 g (10 mmol) of Meldrum s acid are dissolved in 25 ml of pyridine, 5.0 g (10 mmol) of powdered 2,6-diphenyl-4-ethoxytellurinium fluorosulfate are added, and the dark red solution is immediately concentrated under vacuum. TTie residue is chromatographed on 100/200 mesh Florisil with dichloromethane as the mobile phase yield 4.0 g (80%) m.p. 199-201°. 

Die Additionsprodukte von Phenylhydrazonen und l,4-Dioxo-l,4-diphenyl-butin cyclisieren photoche-misch in Benzol Oder Methanol (1 2 mmol in 75 ml). Die Reaktion verlauft fiber eine 2,3-Dihydro-lH-pyrazol-Zwischenstufe, gefolgt von einem Dehydrierschritt967. 

Dimethoxycarbonyl-3,4-diphenyl- 710 4-Butyl-3,5-dioxo-l,2-diphenyl- 405 4-Butyl-3,5-dioxo-l-(4-hydroxy-phenyl)-2-phenyl-... 

Naphthalin-1,8-dicarbonsdure-anhydriderhalt man durch Oxygenierung von Acenaphthen mit Luftsauerstoff zu 80% Ausbeute110. Im Zweiphasensystem Tetrachlormethan/Wasser wird 3,4-Dioxo-l,2-diphenyl-cyclobuten mit waBr. Wasserstoffperoxid in 79% Ausbeute zu Diphenyl-maleinsaure-anhydrid oxygeniert111. 

C3oH2202f meso-2,2 -Dioxo-l,1 -diphenyl-1,r-biindane, 44B, 153 C37H24N4O5, Indan-1,2,3-trione 2-(N-benzoyl-N-phenylhydrazone) indan-1,2,3-trione 2-(N-phenylhydrazone), 44B, 153 C4 3H30O2 f 1-(Diphenylvinylidene)-3-phenyl-2-indenyl diphenylacetate, 45B, 148... 

Dioxo-4,8-diphenyl-l,3,5,7-tetraaza-bicyclof3.3.0]octan laBt sich durch Lithium-alanat in5-Hydroxy-3- phenyl-1,2,4- triazolidin (14% d.Th.), N-Methyl- benzylamin auf-spalten4 ... 

DieKeto- undEnol-Formen von l,3-Dioxo-2-methyl- 1,3-diphenyl-propan liefern ver-schiedene Reduktionsprodukte4 ... 

In einer Photoreaktion reagiert 2,5-Diphenyl-l,3,4-oxadiazol mit l,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin unter Ringspaltung. Das gebildete 5-(a.-Benzoylhydrazono-ben-zyl)-1,3-dimethyl-2.4-dioxo-1.2,3,4-teirahydro-pyrimidm (4 44%) kann zu anderen Folgepro-dukten wciterreagieren78". 

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