Dinitrosyl iron complexes

Mulsch A., Mordvintcev, P. 1., Vanin, A. F., and Busse, R. (1993). Formation and release of dinitrosyl iron complexes by endothelial cells. Biochem. Biophys. Res. Commun. 196, 1303-1308. [Pg.109]

Vanin, A. F., Mordvincev, P. I., Huischildt, S., and Mulsch, A. (1993). The relationship between L-arginine-dependent nitric oxide synthesis, nitrite release and dinitrosyl-iron complex formation by activated macrophages. Biochim. Biophys. Acta 1177, 37-42. [Pg.110]

Special attention was also paid to understanding the basic properties and reactivity patterns of the dinitrosyl iron complexes and Roussin s red salt esters, and to resolve the mechanism of their biological functions and NO emission (43-47). The quantum yield of NO release from [Fe2(p2-SR)2(NO)4] under visible light irradiation can be considerably enhanced by incorporating into the ester a proper chromophore then single- or two-photon processes were observed (46,48,49). [Pg.306]

It is postulated that dinitrosyl iron complexes play an important role in signal transduction pathways regulating the cellular functions [60, 345, 346]. Both low... [Pg.83]

Interactions of Glutathione Transferases and Dinitrosyl Iron Complexes... [Pg.85]

NO in the unbound form has a very short lifetime in the cell but can be stabilized by the formation of complexes, i.e. metal-porphyrin nitrosyls, dinitrosyl-iron complexes and S-nitrosothiols, which are cmisidered to be its biological transporters. Nitric oxide has a very high affinity for iron contained in the active sites of proteins [74]. [Pg.93]

Dai RJ, Ke SC (2007) Detection and determination of the Fe(NO)2 core vibrational features in dinitrosyl-iron complexes from experiment, normal coordinate analysis, and density functional theory an avenue for probing the nitric oxide oxidation state. J Phys Chem B 111 2335-2346... [Pg.96]

Lu TT, Chiou SJ et al (2006) Mononitrosyl tris(thiolate) iron complex [Fe(NO) (SPh)3] and dinitrosyl irrai ctnnplex [(EtS)2Fe(NO)2] formation pathway of dinitrosyl iron complexes (DNICs) frmn nibosylatirai of biomimetic rubredoxin [Fe(SR)4] (R = Ph, Et). Inorg Chem 45 8799-8806... [Pg.98]

Vanin AF (1998) Dinitrosyl iron complexes and S-nitrosothiols are two possible forms for stabilization and transport of nitric oxide in biological systems. Biochemistry 63 782-793... [Pg.98]

Wiegant FA, Malyshev lY et al (1999) Dinitrosyl iron complexes with thiol-containing ligands and S-nitroso-D, L-penicillamine as inductors of heat shock protein synthesis in H35 hepatoma cells. FEBS Lett 455 179-182... [Pg.98]

Tsai FT, Chiou SJ et al (2005) Dinitrosyl iron complexes (DNICs) [L2Fe(NO)2]- (L = Thiolate) interconversion among Fe (NO)2 DNICs, Fe(NO)2 DNICs, and [2Fe-2S] clusters, and the critical role of the thiolate ligands in regulating NO release of DNICs. Inorg Chem 44 5872-5881... [Pg.99]

Vanin AF, Sanina NA et al (2007) Dinitrosyl-iron complexes with thiol-containing ligands spatial and electronic structures. Nitric Oxide 16 82-93... [Pg.100]

Costanzo S, Menage S et al (2001) Re-examination of the formation of dinitrosyl-iron complexes during reaction of S-nitrosothiols with Fe (II). Inorg Chim Acta 318 1-7... [Pg.100]

Sanina NA, Rakova OA et al (2004) Structure of the neutral mononuclear dinitrosyl iron complex with l,2,4-triazole-3-thione[Fe(SC2H3N3)(SC2H2N3)(NO)2]-0.5 H2O. Mendeleev Commun 14 7-8... [Pg.101]

Tsou CC, Lu TT, Liaw WF (2007) EPR, UV-vis, IR, and X-ray demonstration of the anionic dimeric dinitrosyl iron complex[(NO)2Fe(micro-S(t)Bu)2Fe(NO)2] relevance to the products of nitrosylation of cytosolic and mitochondrial aconitases, and high-potential iron proteins. J Am Chem Soc 129 12626-12627... [Pg.101]

Vanin AF, Stukan RA, Manukhina EB (1996) Physical properties of dinitrosyl iron complexes with thiol-containing ligands in relation with their vasodilator activity. Biochim Biophys Acta 1295 5-12... [Pg.101]

Lu TT, Tsou CC et al (2008) Anionic Roussin s Red Esters (RREs) syn-/anti-[Fe(p-SEt) (N0)2] the critical role of thiolate ligands in regulating the transformation of RREs into dinitrosyl iron complexes and the anionic RREs. Inorg Chem 47 6040-6050... [Pg.101]

Lu TT, Lai SH et al (2011) Discrimination of mononuclear and dinuclear dinitrosyl iron complexes (DNICs) by S K-edge X-ray absorption spectroscopy insight into the electronic structure and reactivity of DNICs. Inorg Chem 50 5396-5406... [Pg.101]

Tsai ML, Hsieh CH, Liaw WF (2007) Dinitrosyl iron complexes (DNICs) containing S/N/0 ligation transformation of Roussin s red ester into the neutral Fe(NO)2 DNICs. Inorg Chem 46 5110-5117... [Pg.102]

Lu TT, Huang HW, Liaw WF (2009) Anionic mixed thiolate-sulfide-bridged Roussin s red esters [(NO)2Fe(p-SR)(p-S)Fe(NO)2] (R = Et, Me, Ph) a key intermediate for transformation of dinitrosyl iron complexes (DNICs) to [2Fe-2S] clusters. Inorg Chem 48 9027-9035... [Pg.102]

Tonzetich ZJ, Do LH, Lippard SJ (2009) Dinitrosyl iron complexes relevant to Rieske cluster nitrosylation. J Am Chem Soc 131 7964—7965... [Pg.102]

Chen TN, Lo FC et al (2006) Dinitrosyl iron complexes [E5Fe(NO)2] (E = S, Se) aprecursor of Roussin s black salt [Fe4E3(NO)7]. Inorg Chim Acta 359 2525-2533... [Pg.102]

Shumaev KB, Kosmachevskaya OV et al (2008) Dinitrosyl iron complexes bind with hemoglobin as markers of oxidative stress. Methods Enzymol 436 445-461... [Pg.103]

Timoshin AA, Vanin AF et al (2007) Protein-bound dinitrosyl-iron complexes appearing in blood of rabbit added with a low-molecular dinitrosyl-iron complex EPR studies. Nitric Oxide 16 286-293... [Pg.103]

Lewandowska H, Brzoska K et al (2010) [Dinitrosyl iron complexes-structure and biological functions]. Postepy Biochem 56 298-304... [Pg.111]

Meczynska S, Lewandowska H et al (2008) Variable inhibitory effects on the formation of dinitrosyl iron complexes by deferoxamine and salicylaldehyde isonicotinoyl hydrazone in K562 cells. Hemoglobin 32 157-163... [Pg.111]

Lewandowska H, Meczynska S et al (2007) Crucial role of lysosomal iron in the formation of dinitrosyl iron complexes in vivo. J Biol Inorg Chem 12 345-352... [Pg.111]

Pedersen JZ, De Maria F et al (2007) Glutathione transferases sequester toxic dinitrosyl-iron complexes in cells. A protection mechanism against excess nitric oxide. J Biol Chem 282 6364-6371... [Pg.111]

Vanin AF, Vanin AF (2008) P103. Dinitrosyl iron complexes with thiolate ligands as future medicines. Nitric Oxide 19 67... [Pg.112]

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